Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048499230> ?p ?o ?g. }
- W2048499230 endingPage "36" @default.
- W2048499230 startingPage "25" @default.
- W2048499230 abstract "Isolates of Plasmodium falciparum commonly undergo a large subtelomeric deletion of the right end of chromosome 9 during in vitro cultivation, accompanied by loss of ability to cytoadhere to melanoma cells and greatly lowered gametocyte production. ItG2, an isolate in which cytoadherence is stable, has undergone a subtelomeric deletion of intermediate length on chromosome 9. We show here that the deletions in all non-cytoadherent clones examined have breakpoints within or delete a novel open reading frame (the breakpoint open reading frame, BPORF) that is a unique sequence in the genome. Surprisingly, in ItG2 BPORF has been removed by an additional 15 kb internal deletion in chromosome 9. These results suggest mechanisms to account for the observed frequent deletion of the right arm of chromosome 9 and for the known stability of cytoadherence in ItG2. However, we were unable to detect var genes in this region of the ItG2 genome. We conclude that the product of a novel gene distinct from the var family is implicated in cytoadherence." @default.
- W2048499230 created "2016-06-24" @default.
- W2048499230 creator A5026320334 @default.
- W2048499230 creator A5029737926 @default.
- W2048499230 creator A5042257591 @default.
- W2048499230 creator A5070398012 @default.
- W2048499230 date "1996-11-01" @default.
- W2048499230 modified "2023-10-02" @default.
- W2048499230 title "Disruption of a novel open reading frame of Plasmodium falciparum chromosome 9 by subtelomeric and internal deletions can lead to loss or maintenance of cytoadherence" @default.
- W2048499230 cites W1747642085 @default.
- W2048499230 cites W191400563 @default.
- W2048499230 cites W1965430762 @default.
- W2048499230 cites W1967559279 @default.
- W2048499230 cites W1969503178 @default.
- W2048499230 cites W1980752431 @default.
- W2048499230 cites W1984915289 @default.
- W2048499230 cites W1996090259 @default.
- W2048499230 cites W2002564673 @default.
- W2048499230 cites W2014669590 @default.
- W2048499230 cites W2020637870 @default.
- W2048499230 cites W2021874649 @default.
- W2048499230 cites W2022713916 @default.
- W2048499230 cites W2023018455 @default.
- W2048499230 cites W2032103224 @default.
- W2048499230 cites W2032118018 @default.
- W2048499230 cites W2044973494 @default.
- W2048499230 cites W2049700891 @default.
- W2048499230 cites W2051282315 @default.
- W2048499230 cites W2052523483 @default.
- W2048499230 cites W2059576451 @default.
- W2048499230 cites W2059613312 @default.
- W2048499230 cites W2065019097 @default.
- W2048499230 cites W2073024879 @default.
- W2048499230 cites W2077163521 @default.
- W2048499230 cites W2078495997 @default.
- W2048499230 cites W2078974652 @default.
- W2048499230 cites W2083788953 @default.
- W2048499230 cites W2109816065 @default.
- W2048499230 cites W2118409742 @default.
- W2048499230 cites W2128597754 @default.
- W2048499230 cites W2153277457 @default.
- W2048499230 cites W2156932941 @default.
- W2048499230 cites W2307452791 @default.
- W2048499230 cites W2471260919 @default.
- W2048499230 doi "https://doi.org/10.1016/0166-6851(96)02715-6" @default.
- W2048499230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8943148" @default.
- W2048499230 hasPublicationYear "1996" @default.
- W2048499230 type Work @default.
- W2048499230 sameAs 2048499230 @default.
- W2048499230 citedByCount "32" @default.
- W2048499230 countsByYear W20484992302012 @default.
- W2048499230 countsByYear W20484992302013 @default.
- W2048499230 countsByYear W20484992302016 @default.
- W2048499230 countsByYear W20484992302018 @default.
- W2048499230 countsByYear W20484992302023 @default.
- W2048499230 crossrefType "journal-article" @default.
- W2048499230 hasAuthorship W2048499230A5026320334 @default.
- W2048499230 hasAuthorship W2048499230A5029737926 @default.
- W2048499230 hasAuthorship W2048499230A5042257591 @default.
- W2048499230 hasAuthorship W2048499230A5070398012 @default.
- W2048499230 hasConcept C104317684 @default.
- W2048499230 hasConcept C141231307 @default.
- W2048499230 hasConcept C153911025 @default.
- W2048499230 hasConcept C167625842 @default.
- W2048499230 hasConcept C203014093 @default.
- W2048499230 hasConcept C206936463 @default.
- W2048499230 hasConcept C23069440 @default.
- W2048499230 hasConcept C2778048844 @default.
- W2048499230 hasConcept C2778371730 @default.
- W2048499230 hasConcept C30481170 @default.
- W2048499230 hasConcept C47289529 @default.
- W2048499230 hasConcept C54355233 @default.
- W2048499230 hasConcept C86803240 @default.
- W2048499230 hasConceptScore W2048499230C104317684 @default.
- W2048499230 hasConceptScore W2048499230C141231307 @default.
- W2048499230 hasConceptScore W2048499230C153911025 @default.
- W2048499230 hasConceptScore W2048499230C167625842 @default.
- W2048499230 hasConceptScore W2048499230C203014093 @default.
- W2048499230 hasConceptScore W2048499230C206936463 @default.
- W2048499230 hasConceptScore W2048499230C23069440 @default.
- W2048499230 hasConceptScore W2048499230C2778048844 @default.
- W2048499230 hasConceptScore W2048499230C2778371730 @default.
- W2048499230 hasConceptScore W2048499230C30481170 @default.
- W2048499230 hasConceptScore W2048499230C47289529 @default.
- W2048499230 hasConceptScore W2048499230C54355233 @default.
- W2048499230 hasConceptScore W2048499230C86803240 @default.
- W2048499230 hasIssue "1" @default.
- W2048499230 hasLocation W20484992301 @default.
- W2048499230 hasLocation W20484992302 @default.
- W2048499230 hasOpenAccess W2048499230 @default.
- W2048499230 hasPrimaryLocation W20484992301 @default.
- W2048499230 hasRelatedWork W1525091092 @default.
- W2048499230 hasRelatedWork W1987905608 @default.
- W2048499230 hasRelatedWork W2023018455 @default.
- W2048499230 hasRelatedWork W2031436818 @default.
- W2048499230 hasRelatedWork W2045313050 @default.
- W2048499230 hasRelatedWork W2065019097 @default.
- W2048499230 hasRelatedWork W2088063203 @default.