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• W2048511036 abstract "Wnts are secreted glycoproteins that play important roles in embryonic development. Wnt2b is transiently expressed in the primitive streak (PS) during gastrulation and in several organs during organogenesis. To determine the biological function of Wnt2b during mouse development, we established a conditional null allele of Wnt2b. Mice lacking Wnt2b were viable, fertile, and displayed a normal life span, however, the olfactory bulb in adult Wnt2b mutant mice was significantly reduced in length. Our results suggest that Wnt2b primarily plays a supportive role in gastrulation and organogenesis, functioning redundantly with canonical Wnts, such as Wnt2, in numerous tissues." @default.
• W2048511036 created "2016-06-24" @default.
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• W2048511036 date "2012-03-01" @default.
• W2048511036 modified "2023-10-15" @default.
• W2048511036 title "Mice lacking Wnt2b are viable and display a postnatal olfactory bulb phenotype" @default.
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• W2048511036 doi "https://doi.org/10.1016/j.neulet.2012.01.062" @default.
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