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- W2048585324 abstract "A general characteristic of tumour cells is their unstable karyotype. It is suggested here that maintenance of the normal diploid cell depends on the presence of two copies of specific genes; a change in gene dosage of one or more of these genes, by chromosome nondisjunction or rearrangement, may trigger a general loss of accuracy in chromosome segregation at mitosis." @default.
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- W2048585324 date "1989-01-01" @default.
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- W2048585324 title "Chromosome error propagation and cancer" @default.
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- W2048585324 doi "https://doi.org/10.1016/0168-9525(89)90020-6" @default.
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