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- W2048593285 abstract "The distribution of nucleotides was studied in the various subcellular fractions of rat brain separated by Ficoll density gradient centrifugation. Nucleotides were found in all subcellular fractions, attached primarily to membranous components, with the highest concentration in the nerve ending fraction. By examining the in vivo incorporation of 32Pi into the nucleotides of the subcellular fractions, it could be established that the mitochondrion was the primary site of ATP synthesis and that the pattern of nucleotide distribution was not an artifact of the isolation procedure. Ca2+ appeared to be associated with the lipid component of the fractions, and its accumulation within the fractions and isolated frog spinal ganglia did not appear to be energy-dependent." @default.
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- W2048593285 date "1968-04-01" @default.
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- W2048593285 title "Nucleotide content, calcium accumulation, and phosphate metabolism in subcellular fractions of rat brain" @default.
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- W2048593285 doi "https://doi.org/10.1016/0005-2728(68)90183-7" @default.
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