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• W2048606401 abstract "The blocker of protein kinase C(PKC) activated large-conductance channel(337.1 pS) in cell attached patch mode in cultured vascular smooth muscle cells. The channel showed time-dependent inactivation whose time course became faster as the amplitude of the command potential was increased. These characteristics of large-conductance channel activated by the application of the PKC blocker were very similar to those of voltage-dependent Cl channels in these cells, indicating the channel activated by the drug is Cl channel. Since voltage-dependent Cl channels were reported to be only activated by forming inside-out patch, these findings suggest Cl permeability of vascular smooth muscle cells is at least partially regulated by protein kinase C." @default.
• W2048606401 created "2016-06-24" @default.
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• W2048606401 date "1988-09-01" @default.
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• W2048606401 title "Protein kinase c may regulate resting anion conductance in vascular smooth muscle cells" @default.
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• W2048606401 doi "https://doi.org/10.1016/s0006-291x(88)80578-3" @default.
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