FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048607595> ?p ?o ?g. }

• W2048607595 endingPage "135" @default.
• W2048607595 startingPage "129" @default.
• W2048607595 abstract "We have investigated the Cu2+ induced generation of lipid peroxides in low density lipoprotein (LDL) incubated with high density lipoprotein (HDL) and with purified paraoxonase, an enzyme normally resident on HDL. HDL (1.5 mg) and paraoxonase (20 micrograms) inhibited lipid peroxide generation in LDL by 32% and 25%, respectively after 24 h of incubation (both P < 0.01). The decrease in LDL lipid peroxides both with HDL and with paraoxonase were concentration dependent. The degree of protection offered by HDL tended to relate to its paraoxonase activity (R = 0.47; P < 0.06). Neither purified paraoxonase nor HDL chelated Cu2+ sufficiently to account for the decrease in LDL oxidation. Purified paraoxonase did not affect LDL oxidation when it had been heat inactivated. Mass transfer of lipid peroxides from LDL to HDL did not explain the protection of LDL against oxidation: the total lipid peroxides accumulating during incubation was decreased both by HDL and by paraoxonase. These results suggest a direct role for HDL in preventing atherosclerosis probably by an enzymic process which prevents the accumulation of lipid peroxides on LDL. Paraoxonase is an example of an enzyme which might possibly be involved." @default.
• W2048607595 created "2016-06-24" @default.
• W2048607595 creator A5003044776 @default.
• W2048607595 creator A5070436463 @default.
• W2048607595 creator A5086859309 @default.
• W2048607595 creator A5090251071 @default.
• W2048607595 date "1993-12-01" @default.
• W2048607595 modified "2023-09-26" @default.
• W2048607595 title "Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase" @default.
• W2048607595 cites W1484256975 @default.
• W2048607595 cites W1502167224 @default.
• W2048607595 cites W1536008717 @default.
• W2048607595 cites W1544584829 @default.
• W2048607595 cites W1841006369 @default.
• W2048607595 cites W1857052429 @default.
• W2048607595 cites W1878775584 @default.
• W2048607595 cites W1906942130 @default.
• W2048607595 cites W1987683192 @default.
• W2048607595 cites W1992335027 @default.
• W2048607595 cites W2009117465 @default.
• W2048607595 cites W2042203706 @default.
• W2048607595 cites W2046946523 @default.
• W2048607595 cites W2061663562 @default.
• W2048607595 cites W2081406581 @default.
• W2048607595 cites W2085600362 @default.
• W2048607595 cites W2101092993 @default.
• W2048607595 cites W2105194226 @default.
• W2048607595 cites W2169032178 @default.
• W2048607595 cites W2238521482 @default.
• W2048607595 cites W2254923557 @default.
• W2048607595 cites W3022864527 @default.
• W2048607595 cites W50269454 @default.
• W2048607595 cites W563924022 @default.
• W2048607595 cites W622977380 @default.
• W2048607595 doi "https://doi.org/10.1016/0021-9150(93)90183-u" @default.
• W2048607595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8141836" @default.
• W2048607595 hasPublicationYear "1993" @default.
• W2048607595 type Work @default.
• W2048607595 sameAs 2048607595 @default.
• W2048607595 citedByCount "748" @default.
• W2048607595 countsByYear W20486075952012 @default.
• W2048607595 countsByYear W20486075952013 @default.
• W2048607595 countsByYear W20486075952014 @default.
• W2048607595 countsByYear W20486075952015 @default.
• W2048607595 countsByYear W20486075952016 @default.
• W2048607595 countsByYear W20486075952017 @default.
• W2048607595 countsByYear W20486075952018 @default.
• W2048607595 countsByYear W20486075952019 @default.
• W2048607595 countsByYear W20486075952020 @default.
• W2048607595 countsByYear W20486075952021 @default.
• W2048607595 countsByYear W20486075952022 @default.
• W2048607595 countsByYear W20486075952023 @default.
• W2048607595 crossrefType "journal-article" @default.
• W2048607595 hasAuthorship W2048607595A5003044776 @default.
• W2048607595 hasAuthorship W2048607595A5070436463 @default.
• W2048607595 hasAuthorship W2048607595A5086859309 @default.
• W2048607595 hasAuthorship W2048607595A5090251071 @default.
• W2048607595 hasConcept C104317684 @default.
• W2048607595 hasConcept C126322002 @default.
• W2048607595 hasConcept C134018914 @default.
• W2048607595 hasConcept C135763542 @default.
• W2048607595 hasConcept C181199279 @default.
• W2048607595 hasConcept C185592680 @default.
• W2048607595 hasConcept C25642318 @default.
• W2048607595 hasConcept C2776509667 @default.
• W2048607595 hasConcept C2778163477 @default.
• W2048607595 hasConcept C2778242859 @default.
• W2048607595 hasConcept C2779620165 @default.
• W2048607595 hasConcept C2780072125 @default.
• W2048607595 hasConcept C2780541478 @default.
• W2048607595 hasConcept C2780829032 @default.
• W2048607595 hasConcept C2993790521 @default.
• W2048607595 hasConcept C37501387 @default.
• W2048607595 hasConcept C55493867 @default.
• W2048607595 hasConcept C57600042 @default.
• W2048607595 hasConcept C71924100 @default.
• W2048607595 hasConcept C86803240 @default.
• W2048607595 hasConceptScore W2048607595C104317684 @default.
• W2048607595 hasConceptScore W2048607595C126322002 @default.
• W2048607595 hasConceptScore W2048607595C134018914 @default.
• W2048607595 hasConceptScore W2048607595C135763542 @default.
• W2048607595 hasConceptScore W2048607595C181199279 @default.
• W2048607595 hasConceptScore W2048607595C185592680 @default.
• W2048607595 hasConceptScore W2048607595C25642318 @default.
• W2048607595 hasConceptScore W2048607595C2776509667 @default.
• W2048607595 hasConceptScore W2048607595C2778163477 @default.
• W2048607595 hasConceptScore W2048607595C2778242859 @default.
• W2048607595 hasConceptScore W2048607595C2779620165 @default.
• W2048607595 hasConceptScore W2048607595C2780072125 @default.
• W2048607595 hasConceptScore W2048607595C2780541478 @default.
• W2048607595 hasConceptScore W2048607595C2780829032 @default.
• W2048607595 hasConceptScore W2048607595C2993790521 @default.
• W2048607595 hasConceptScore W2048607595C37501387 @default.
• W2048607595 hasConceptScore W2048607595C55493867 @default.
• W2048607595 hasConceptScore W2048607595C57600042 @default.
• W2048607595 hasConceptScore W2048607595C71924100 @default.
• W2048607595 hasConceptScore W2048607595C86803240 @default.
• W2048607595 hasIssue "1-2" @default.

• next