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- W2048611387 abstract "Epilepsy with myoclonic absences (EMA) is a rare epileptic syndrome with frequently poor response to antiepileptic treatment. Rufinamide (RUF) is a relatively new EMEA- and FDA-approved anticonvulsant licensed as an orphan drug for the adjunctive treatment of patients with Lennox-Gastaut syndrome.A retrospective data analysis in 3 patients was performed.Add-on RUF treatment was initiated in 3 boys with EMA refractory to conventional antiepileptic therapy (primidone + valproic acid, n=1; levetiracetame + ethosuximide, n=2). It resulted in complete cessation of all seizures in 2, and a 50% reduction of the seizure frequency in one child, respectively.RUF add-on therapy should be considered in children with EMA not responding to conventional antiepileptic therapy." @default.
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- W2048611387 date "2011-02-01" @default.
- W2048611387 modified "2023-10-18" @default.
- W2048611387 title "Epilepsy with Myoclonic Absences – Favourable Response to Add-on Rufinamide Treatment in 3 Cases" @default.
- W2048611387 doi "https://doi.org/10.1055/s-0031-1275346" @default.
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