Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048654072> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2048654072 endingPage "634" @default.
- W2048654072 startingPage "629" @default.
- W2048654072 abstract "1. An enzyme has been partially purified from Ehrlich ascites tumour cells which specifically hydrolyses dinucleosidetetraphosphates, with Km values of around 2 μM. The products of the hydrolysis are the corresponding nucleoside tri- and monophosphates. Dinucleoside tri- and diphosphates were not substrates of the reaction. 2. The enzyme requires Mg2+ or Mn2+, is maximally active at a pH value of approx. 7.5 and has a mol. wt of 19,800 as estimated by filtration on Sephadex G-75. Nucleoside mono-, di- and triphosphates were competitive inhibitors of the reaction with Ki values in the 0.1 mM range. 3. Particularly relevant is the inhibition of this enzyme by adenosine and guanosine 5'-tetraphos-phates. In the course of this investigation, the presence of uridine 5'-tetraphosphate was detected in a commercial preparation of UTP. Adenosine, guanosine and uridine 5'-tetraphosphates were very strong inhibitors of the reaction with Ki values in the nM range." @default.
- W2048654072 created "2016-06-24" @default.
- W2048654072 creator A5002793455 @default.
- W2048654072 creator A5012000879 @default.
- W2048654072 creator A5019316563 @default.
- W2048654072 creator A5084105545 @default.
- W2048654072 date "1982-01-01" @default.
- W2048654072 modified "2023-09-26" @default.
- W2048654072 title "Dinucleosidetetraphosphatase from ehrlich ascites tumour cells: Inhibition by adenosine, guanosine and uridine 5'-tetraphosphates" @default.
- W2048654072 cites W1529583012 @default.
- W2048654072 cites W1623269528 @default.
- W2048654072 cites W166180316 @default.
- W2048654072 cites W1968611585 @default.
- W2048654072 cites W1969883995 @default.
- W2048654072 cites W1999966625 @default.
- W2048654072 cites W2023407552 @default.
- W2048654072 cites W2024134142 @default.
- W2048654072 cites W2029589878 @default.
- W2048654072 cites W2040520370 @default.
- W2048654072 cites W2044112756 @default.
- W2048654072 cites W2065073389 @default.
- W2048654072 cites W2067915456 @default.
- W2048654072 cites W2084113205 @default.
- W2048654072 cites W2123775212 @default.
- W2048654072 cites W2153435210 @default.
- W2048654072 doi "https://doi.org/10.1016/0020-711x(82)90047-7" @default.
- W2048654072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6286385" @default.
- W2048654072 hasPublicationYear "1982" @default.
- W2048654072 type Work @default.
- W2048654072 sameAs 2048654072 @default.
- W2048654072 citedByCount "40" @default.
- W2048654072 countsByYear W20486540722018 @default.
- W2048654072 countsByYear W20486540722020 @default.
- W2048654072 crossrefType "journal-article" @default.
- W2048654072 hasAuthorship W2048654072A5002793455 @default.
- W2048654072 hasAuthorship W2048654072A5012000879 @default.
- W2048654072 hasAuthorship W2048654072A5019316563 @default.
- W2048654072 hasAuthorship W2048654072A5084105545 @default.
- W2048654072 hasConcept C104317684 @default.
- W2048654072 hasConcept C118716 @default.
- W2048654072 hasConcept C163994747 @default.
- W2048654072 hasConcept C181199279 @default.
- W2048654072 hasConcept C185592680 @default.
- W2048654072 hasConcept C18880352 @default.
- W2048654072 hasConcept C2776543447 @default.
- W2048654072 hasConcept C2776638253 @default.
- W2048654072 hasConcept C2776991684 @default.
- W2048654072 hasConcept C2777995097 @default.
- W2048654072 hasConcept C2781184954 @default.
- W2048654072 hasConcept C2781259782 @default.
- W2048654072 hasConcept C55493867 @default.
- W2048654072 hasConcept C67705224 @default.
- W2048654072 hasConcept C71240020 @default.
- W2048654072 hasConcept C94412978 @default.
- W2048654072 hasConceptScore W2048654072C104317684 @default.
- W2048654072 hasConceptScore W2048654072C118716 @default.
- W2048654072 hasConceptScore W2048654072C163994747 @default.
- W2048654072 hasConceptScore W2048654072C181199279 @default.
- W2048654072 hasConceptScore W2048654072C185592680 @default.
- W2048654072 hasConceptScore W2048654072C18880352 @default.
- W2048654072 hasConceptScore W2048654072C2776543447 @default.
- W2048654072 hasConceptScore W2048654072C2776638253 @default.
- W2048654072 hasConceptScore W2048654072C2776991684 @default.
- W2048654072 hasConceptScore W2048654072C2777995097 @default.
- W2048654072 hasConceptScore W2048654072C2781184954 @default.
- W2048654072 hasConceptScore W2048654072C2781259782 @default.
- W2048654072 hasConceptScore W2048654072C55493867 @default.
- W2048654072 hasConceptScore W2048654072C67705224 @default.
- W2048654072 hasConceptScore W2048654072C71240020 @default.
- W2048654072 hasConceptScore W2048654072C94412978 @default.
- W2048654072 hasIssue "7" @default.
- W2048654072 hasLocation W20486540721 @default.
- W2048654072 hasLocation W20486540722 @default.
- W2048654072 hasOpenAccess W2048654072 @default.
- W2048654072 hasPrimaryLocation W20486540721 @default.
- W2048654072 hasRelatedWork W1592674763 @default.
- W2048654072 hasRelatedWork W1965023463 @default.
- W2048654072 hasRelatedWork W1968374069 @default.
- W2048654072 hasRelatedWork W1973335819 @default.
- W2048654072 hasRelatedWork W2025019305 @default.
- W2048654072 hasRelatedWork W2031608471 @default.
- W2048654072 hasRelatedWork W2048654072 @default.
- W2048654072 hasRelatedWork W2085667785 @default.
- W2048654072 hasRelatedWork W2085832734 @default.
- W2048654072 hasRelatedWork W2126995955 @default.
- W2048654072 hasVolume "14" @default.
- W2048654072 isParatext "false" @default.
- W2048654072 isRetracted "false" @default.
- W2048654072 magId "2048654072" @default.
- W2048654072 workType "article" @default.