Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048655040> ?p ?o ?g. }
- W2048655040 endingPage "1800" @default.
- W2048655040 startingPage "1789" @default.
- W2048655040 abstract "Introduction: In 2010, about 8.8 million new cases of tuberculosis were recorded and 1.1 million people died of tuberculosis worldwide. Although numbers are in decrease since 2006, tuberculosis still represents a global issue and a major public health threat, due to appearance of multidrug-resistant and extensively drug-resistant tuberculosis cases. Although anti-tuberculosis drugs currently used are effective against tuberculosis, they present however more and more limits, especially in treating complex cases of tuberculosis, increasing therefore the need to develop new tools and approaches to treat tuberculosis today. Areas covered: In this review, we describe anti-tuberculosis drugs in Phase II clinical trials and in preclinical phase that are likely to play a crucial role in the management of tuberculosis cases in a near future. SQ109, TMC207, nitroimidazoles, and oxazolidinones are currently in Phase II clinical trials while BDM31343, SQ641, CPZEN-45, RBx 8700, DC-159a, and BTZ043 are in preclinical phase. Conclusion: These drugs, alone or in different combinations represent a promising future for the treatment of tuberculosis. Continual conjugative efforts between governments and private organizations worldwide are essential for building new strategies for discovery and the development of new anti-tuberculosis drugs." @default.
- W2048655040 created "2016-06-24" @default.
- W2048655040 creator A5038751055 @default.
- W2048655040 date "2012-09-19" @default.
- W2048655040 modified "2023-10-18" @default.
- W2048655040 title "Antimycobacterial drugs currently in Phase II clinical trials and preclinical phase for tuberculosis treatment" @default.
- W2048655040 cites W1538374398 @default.
- W2048655040 cites W1777034581 @default.
- W2048655040 cites W1930402573 @default.
- W2048655040 cites W1966642070 @default.
- W2048655040 cites W1966758779 @default.
- W2048655040 cites W1969586092 @default.
- W2048655040 cites W1976256007 @default.
- W2048655040 cites W1978146833 @default.
- W2048655040 cites W1981198757 @default.
- W2048655040 cites W1987722702 @default.
- W2048655040 cites W1987864694 @default.
- W2048655040 cites W1993063963 @default.
- W2048655040 cites W1996794817 @default.
- W2048655040 cites W2013159525 @default.
- W2048655040 cites W2016620483 @default.
- W2048655040 cites W2019872023 @default.
- W2048655040 cites W2034077454 @default.
- W2048655040 cites W2039924198 @default.
- W2048655040 cites W2067345781 @default.
- W2048655040 cites W2068399458 @default.
- W2048655040 cites W2072721264 @default.
- W2048655040 cites W2081675900 @default.
- W2048655040 cites W2084062265 @default.
- W2048655040 cites W2089446233 @default.
- W2048655040 cites W2091019485 @default.
- W2048655040 cites W2091447314 @default.
- W2048655040 cites W2093907473 @default.
- W2048655040 cites W2098146193 @default.
- W2048655040 cites W2103620979 @default.
- W2048655040 cites W2104750364 @default.
- W2048655040 cites W2109938551 @default.
- W2048655040 cites W2116644805 @default.
- W2048655040 cites W2119762586 @default.
- W2048655040 cites W2120833699 @default.
- W2048655040 cites W2125239816 @default.
- W2048655040 cites W2126481020 @default.
- W2048655040 cites W2128796998 @default.
- W2048655040 cites W2129759335 @default.
- W2048655040 cites W2132748184 @default.
- W2048655040 cites W2133587820 @default.
- W2048655040 cites W2134320523 @default.
- W2048655040 cites W2134476763 @default.
- W2048655040 cites W2135027892 @default.
- W2048655040 cites W2136311709 @default.
- W2048655040 cites W2138724425 @default.
- W2048655040 cites W2139097820 @default.
- W2048655040 cites W2140862820 @default.
- W2048655040 cites W2143564574 @default.
- W2048655040 cites W2145085703 @default.
- W2048655040 cites W2145513267 @default.
- W2048655040 cites W2147746385 @default.
- W2048655040 cites W2149415226 @default.
- W2048655040 cites W2150324756 @default.
- W2048655040 cites W2154166649 @default.
- W2048655040 cites W2155375392 @default.
- W2048655040 cites W2158530209 @default.
- W2048655040 cites W2158658436 @default.
- W2048655040 cites W2164791362 @default.
- W2048655040 cites W2164918529 @default.
- W2048655040 cites W2167163155 @default.
- W2048655040 cites W2169800706 @default.
- W2048655040 cites W2181194591 @default.
- W2048655040 doi "https://doi.org/10.1517/13543784.2012.724397" @default.
- W2048655040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22991970" @default.
- W2048655040 hasPublicationYear "2012" @default.
- W2048655040 type Work @default.
- W2048655040 sameAs 2048655040 @default.
- W2048655040 citedByCount "32" @default.
- W2048655040 countsByYear W20486550402013 @default.
- W2048655040 countsByYear W20486550402014 @default.
- W2048655040 countsByYear W20486550402015 @default.
- W2048655040 countsByYear W20486550402016 @default.
- W2048655040 countsByYear W20486550402017 @default.
- W2048655040 countsByYear W20486550402018 @default.
- W2048655040 countsByYear W20486550402019 @default.
- W2048655040 countsByYear W20486550402021 @default.
- W2048655040 countsByYear W20486550402023 @default.
- W2048655040 crossrefType "journal-article" @default.
- W2048655040 hasAuthorship W2048655040A5038751055 @default.
- W2048655040 hasConcept C126322002 @default.
- W2048655040 hasConcept C142724271 @default.
- W2048655040 hasConcept C177713679 @default.
- W2048655040 hasConcept C2777975735 @default.
- W2048655040 hasConcept C2781069245 @default.
- W2048655040 hasConcept C535046627 @default.
- W2048655040 hasConcept C71924100 @default.
- W2048655040 hasConcept C98274493 @default.
- W2048655040 hasConceptScore W2048655040C126322002 @default.
- W2048655040 hasConceptScore W2048655040C142724271 @default.
- W2048655040 hasConceptScore W2048655040C177713679 @default.
- W2048655040 hasConceptScore W2048655040C2777975735 @default.
- W2048655040 hasConceptScore W2048655040C2781069245 @default.