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• W2048657456 abstract "The synthesis of 6,6-difluoroshikimic acid (11) has been achieved in ten steps from the enantiopure diol 16, which is derived from enzymatic cis-dihydroxylation of iodobenzene. The versatility of the synthetic strategy has been demonstrated by the preparation of the known antimicrobial agent, (6S)-6-fluoroshikimic acid (5)." @default.
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• W2048657456 date "2006-05-01" @default.
• W2048657456 modified "2023-10-18" @default.
• W2048657456 title "Arene cis-dihydrodiols—useful precursors for the preparation of antimetabolites of the shikimic acid pathway: application to the synthesis of 6,6-difluoroshikimic acid and (6S)-6-fluoroshikimic acid" @default.
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• W2048657456 doi "https://doi.org/10.1016/j.tet.2006.03.029" @default.
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