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- W2048687101 endingPage "816" @default.
- W2048687101 startingPage "803" @default.
- W2048687101 abstract "Until recently, it was though that the microbial degradation of aromatic compounds was absolutely dependent on the use of molecular oxygen for ring cleavage. However, as described here by Fuchs and colleagues, microorganisms have other ways of breaking down these compounds when oxygen is scarce or absent. Aromatic compounds are both common growth substrates for microorganisms and prominent environmental pollutants. The crucial step in their degradation is overcoming the resonance energy that stabilizes the ring structure. The classical strategy for degradation comprises an attack by oxygenases that hydroxylate and finally cleave the ring with the help of activated molecular oxygen. Here, we describe three alternative strategies used by microorganisms to degrade aromatic compounds. All three of these methods involve the use of CoA thioesters and ring cleavage by hydrolysis. However, these strategies are based on different ring activation mechanisms that consist of either formation of a non-aromatic ring-epoxide under oxic conditions, or reduction of the aromatic ring under anoxic conditions using one of two completely different systems." @default.
- W2048687101 created "2016-06-24" @default.
- W2048687101 creator A5067757516 @default.
- W2048687101 creator A5072628229 @default.
- W2048687101 creator A5077445480 @default.
- W2048687101 date "2011-10-03" @default.
- W2048687101 modified "2023-10-18" @default.
- W2048687101 title "Microbial degradation of aromatic compounds — from one strategy to four" @default.
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