FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048688848> ?p ?o ?g. }

• W2048688848 abstract "Synonymous codons are used differentially in organisms from the three domains of life, a phenomenon referred to as codon usage bias. In addition, codon pair bias, particularly in the 3’ codon context, has also been described in several organisms and is associated with the accuracy and rate of translation. An improved understanding of both types of bias is important for the optimization of heterologous protein expression, particularly in biotechnologically important organisms, such as the yeast Xanthophyllomyces dendrorhous, a promising bioresource for the carotenoid astaxanthin. Using genomic and transcriptomic data, the codon usage and codon context biases of X. dendrorhous open reading frames (ORFs) were analyzed to determine their expression levels, GC% and sequence lengths. X. dendrorhous totiviral ORFs were also included in these analyses. A total of 1,695 X. dendrorhous ORFs were identified through comparison with sequences in multiple databases, and the intron-exon structures of these sequences were determined. Although there were important expression variations among the ORFs under the studied conditions (different phases of growth and available carbon sources), most of these sequences were highly expressed under at least one of the analyzed conditions. Independent of the culture conditions, the highly expressed genes showed a strong bias in both codon usage and the 3’ context, with a minor association with the GC% and no relationship to the sequence length. The codon usage and codon-pair bias of the totiviral ORFs were highly variable with no similarities to the host ORFs. There is a direct relation between the level of gene expression and codon usage and 3′ context bias in X. dendrorhous, which is more evident for ORFs that are expressed at the highest levels under the studied conditions. However, there is no direct relation between the totiviral ORF biases and the host ORFs." @default.
• W2048688848 created "2016-06-24" @default.
• W2048688848 creator A5024705447 @default.
• W2048688848 creator A5047810254 @default.
• W2048688848 creator A5077608946 @default.
• W2048688848 creator A5077775619 @default.
• W2048688848 creator A5090656094 @default.
• W2048688848 date "2015-04-13" @default.
• W2048688848 modified "2023-10-13" @default.
• W2048688848 title "Codon usage and codon context bias in Xanthophyllomyces dendrorhous" @default.
• W2048688848 cites W1561396590 @default.
• W2048688848 cites W1603411458 @default.
• W2048688848 cites W1827567297 @default.
• W2048688848 cites W1876019739 @default.
• W2048688848 cites W1966367609 @default.
• W2048688848 cites W1967656821 @default.
• W2048688848 cites W1972312652 @default.
• W2048688848 cites W1975686505 @default.
• W2048688848 cites W1977790594 @default.
• W2048688848 cites W1978006472 @default.
• W2048688848 cites W1993358499 @default.
• W2048688848 cites W2000898218 @default.
• W2048688848 cites W2007087540 @default.
• W2048688848 cites W2008963437 @default.
• W2048688848 cites W2009674410 @default.
• W2048688848 cites W2014994812 @default.
• W2048688848 cites W2018731916 @default.
• W2048688848 cites W2019012467 @default.
• W2048688848 cites W2023181696 @default.
• W2048688848 cites W2023622324 @default.
• W2048688848 cites W2032265205 @default.
• W2048688848 cites W2032791509 @default.
• W2048688848 cites W2048685310 @default.
• W2048688848 cites W2051043527 @default.
• W2048688848 cites W2060481089 @default.
• W2048688848 cites W2063504601 @default.
• W2048688848 cites W2066829062 @default.
• W2048688848 cites W2070765702 @default.
• W2048688848 cites W2078146553 @default.
• W2048688848 cites W2094816155 @default.
• W2048688848 cites W2098246182 @default.
• W2048688848 cites W2101551832 @default.
• W2048688848 cites W2103091054 @default.
• W2048688848 cites W2105524011 @default.
• W2048688848 cites W2107644675 @default.
• W2048688848 cites W2108926990 @default.
• W2048688848 cites W2112689874 @default.
• W2048688848 cites W2125076649 @default.
• W2048688848 cites W2128742161 @default.
• W2048688848 cites W2131903353 @default.
• W2048688848 cites W2134541788 @default.
• W2048688848 cites W2140137730 @default.
• W2048688848 cites W2147126179 @default.
• W2048688848 cites W2148734328 @default.
• W2048688848 cites W2151373788 @default.
• W2048688848 cites W2154431984 @default.
• W2048688848 cites W2157848631 @default.
• W2048688848 cites W2159365979 @default.
• W2048688848 cites W2164154943 @default.
• W2048688848 cites W2164618276 @default.
• W2048688848 cites W2169001593 @default.
• W2048688848 cites W2171890843 @default.
• W2048688848 cites W3146979069 @default.
• W2048688848 cites W4213225796 @default.
• W2048688848 cites W85796967 @default.
• W2048688848 doi "https://doi.org/10.1186/s12864-015-1493-5" @default.
• W2048688848 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4404019" @default.
• W2048688848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25887493" @default.
• W2048688848 hasPublicationYear "2015" @default.
• W2048688848 type Work @default.
• W2048688848 sameAs 2048688848 @default.
• W2048688848 citedByCount "29" @default.
• W2048688848 countsByYear W20486888482015 @default.
• W2048688848 countsByYear W20486888482016 @default.
• W2048688848 countsByYear W20486888482017 @default.
• W2048688848 countsByYear W20486888482018 @default.
• W2048688848 countsByYear W20486888482019 @default.
• W2048688848 countsByYear W20486888482020 @default.
• W2048688848 countsByYear W20486888482021 @default.
• W2048688848 countsByYear W20486888482022 @default.
• W2048688848 countsByYear W20486888482023 @default.
• W2048688848 crossrefType "journal-article" @default.
• W2048688848 hasAuthorship W2048688848A5024705447 @default.
• W2048688848 hasAuthorship W2048688848A5047810254 @default.
• W2048688848 hasAuthorship W2048688848A5077608946 @default.
• W2048688848 hasAuthorship W2048688848A5077775619 @default.
• W2048688848 hasAuthorship W2048688848A5090656094 @default.
• W2048688848 hasBestOaLocation W20486888481 @default.
• W2048688848 hasConcept C104317684 @default.
• W2048688848 hasConcept C105580179 @default.
• W2048688848 hasConcept C141231307 @default.
• W2048688848 hasConcept C149364088 @default.
• W2048688848 hasConcept C151730666 @default.
• W2048688848 hasConcept C167625842 @default.
• W2048688848 hasConcept C2775992057 @default.
• W2048688848 hasConcept C2779343474 @default.
• W2048688848 hasConcept C2780530800 @default.
• W2048688848 hasConcept C47289529 @default.
• W2048688848 hasConcept C54355233 @default.
• W2048688848 hasConcept C86803240 @default.

• next