Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048703659> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2048703659 endingPage "89" @default.
- W2048703659 startingPage "86" @default.
- W2048703659 abstract "Ferritin is the main protein devoted to iron storage in living systems. Several evidences show that ferritin can bind in vivo metals other than iron, such as aluminium. Moreover, recent studies demonstrated that ferritin iron core composition differs between physiological and pathological brain ferritins. The precise evaluation of chemical species present within the ferritin mineral core and their chemical coordination is therefore of paramount importance. X-ray photoelectron spectroscopy and energy dispersive X-ray spectroscopy are powerful tools to perform this chemical analysis: however the protein shell surrounding the mineral core reduces significantly the amount of electrons/photons detected, thus reducing the potentiality of these techniques. In this framework we investigated the use of physical treatments, namely focused ion beam milling and oxygen plasma etching, in order to overcome the limitations imposed by the presence of the protein shell. We demonstrated that the combined use of focused ion beam milling and energy dispersive X-ray spectroscopy provides an enhancement of iron detection by a factor of about two. As for the X-ray photoelectron spectroscopy technique, it has an intrinsic low capability of probing the core metal in ferritin due to the electron escape depth value that is of the order of the protein shell thickness. Using a pre-treatment in oxygen plasma the detection of iron was enhanced by a factor of more than 15. Therefore, the disruption of the protein shell by plasma etching or ion milling emerges as a fundamental prerequisite to perform an accurate chemical characterization of the ferritin core." @default.
- W2048703659 created "2016-06-24" @default.
- W2048703659 creator A5009568297 @default.
- W2048703659 creator A5023211640 @default.
- W2048703659 creator A5066334907 @default.
- W2048703659 creator A5067038934 @default.
- W2048703659 date "2014-07-01" @default.
- W2048703659 modified "2023-10-03" @default.
- W2048703659 title "Ion and plasma based treatments for enhanced chemical speciation of metals in ferritin" @default.
- W2048703659 cites W1601516657 @default.
- W2048703659 cites W1977015023 @default.
- W2048703659 cites W2053795256 @default.
- W2048703659 cites W2058565226 @default.
- W2048703659 cites W2084269871 @default.
- W2048703659 cites W2086567353 @default.
- W2048703659 cites W2095344727 @default.
- W2048703659 cites W2113236375 @default.
- W2048703659 cites W48352516 @default.
- W2048703659 doi "https://doi.org/10.1016/j.mee.2014.06.003" @default.
- W2048703659 hasPublicationYear "2014" @default.
- W2048703659 type Work @default.
- W2048703659 sameAs 2048703659 @default.
- W2048703659 citedByCount "5" @default.
- W2048703659 countsByYear W20487036592014 @default.
- W2048703659 countsByYear W20487036592015 @default.
- W2048703659 countsByYear W20487036592016 @default.
- W2048703659 crossrefType "journal-article" @default.
- W2048703659 hasAuthorship W2048703659A5009568297 @default.
- W2048703659 hasAuthorship W2048703659A5023211640 @default.
- W2048703659 hasAuthorship W2048703659A5066334907 @default.
- W2048703659 hasAuthorship W2048703659A5067038934 @default.
- W2048703659 hasConcept C100460472 @default.
- W2048703659 hasConcept C102404424 @default.
- W2048703659 hasConcept C107872376 @default.
- W2048703659 hasConcept C113196181 @default.
- W2048703659 hasConcept C121332964 @default.
- W2048703659 hasConcept C127413603 @default.
- W2048703659 hasConcept C145148216 @default.
- W2048703659 hasConcept C171250308 @default.
- W2048703659 hasConcept C175708663 @default.
- W2048703659 hasConcept C178790620 @default.
- W2048703659 hasConcept C185592680 @default.
- W2048703659 hasConcept C192562407 @default.
- W2048703659 hasConcept C2778319317 @default.
- W2048703659 hasConcept C2779227376 @default.
- W2048703659 hasConcept C32891209 @default.
- W2048703659 hasConcept C42360764 @default.
- W2048703659 hasConcept C513153333 @default.
- W2048703659 hasConcept C55493867 @default.
- W2048703659 hasConcept C62520636 @default.
- W2048703659 hasConceptScore W2048703659C100460472 @default.
- W2048703659 hasConceptScore W2048703659C102404424 @default.
- W2048703659 hasConceptScore W2048703659C107872376 @default.
- W2048703659 hasConceptScore W2048703659C113196181 @default.
- W2048703659 hasConceptScore W2048703659C121332964 @default.
- W2048703659 hasConceptScore W2048703659C127413603 @default.
- W2048703659 hasConceptScore W2048703659C145148216 @default.
- W2048703659 hasConceptScore W2048703659C171250308 @default.
- W2048703659 hasConceptScore W2048703659C175708663 @default.
- W2048703659 hasConceptScore W2048703659C178790620 @default.
- W2048703659 hasConceptScore W2048703659C185592680 @default.
- W2048703659 hasConceptScore W2048703659C192562407 @default.
- W2048703659 hasConceptScore W2048703659C2778319317 @default.
- W2048703659 hasConceptScore W2048703659C2779227376 @default.
- W2048703659 hasConceptScore W2048703659C32891209 @default.
- W2048703659 hasConceptScore W2048703659C42360764 @default.
- W2048703659 hasConceptScore W2048703659C513153333 @default.
- W2048703659 hasConceptScore W2048703659C55493867 @default.
- W2048703659 hasConceptScore W2048703659C62520636 @default.
- W2048703659 hasLocation W20487036591 @default.
- W2048703659 hasOpenAccess W2048703659 @default.
- W2048703659 hasPrimaryLocation W20487036591 @default.
- W2048703659 hasRelatedWork W1983962185 @default.
- W2048703659 hasRelatedWork W2024422983 @default.
- W2048703659 hasRelatedWork W2041748642 @default.
- W2048703659 hasRelatedWork W2045341708 @default.
- W2048703659 hasRelatedWork W2064094521 @default.
- W2048703659 hasRelatedWork W2091008427 @default.
- W2048703659 hasRelatedWork W2172224723 @default.
- W2048703659 hasRelatedWork W2973974236 @default.
- W2048703659 hasRelatedWork W4247851453 @default.
- W2048703659 hasRelatedWork W771314663 @default.
- W2048703659 hasVolume "124" @default.
- W2048703659 isParatext "false" @default.
- W2048703659 isRetracted "false" @default.
- W2048703659 magId "2048703659" @default.
- W2048703659 workType "article" @default.