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- W2048710746 abstract "We read with interest the study by Jeffres and colleagues (October 2006)1 investigating the relationship between vancomycin pharmacokinetic (PK) indices and outcome in patients with confirmed Staphylococcus aureus pneumonia. This study did not find a correlation between vancomycin area under the curve (AUC) ≥ 400 μg/h/mL and hospital mortality in patients with S aureus pneumonia. While the authors acknowledge that previous clinical studies show an association between vancomycin PK indices and patient outcomes, they do not further clarify that the AUC/minimum inhibitory concentration (MIC) ratio and not AUC alone, as evaluated in the current study, has correlated better with patient outcomes in those studies." @default.
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- W2048710746 date "2007-09-01" @default.
- W2048710746 modified "2023-09-24" @default.
- W2048710746 title "Appropriate Pharmacokinetic Index for Outcome in Staphylococcus aureus Pneumonia" @default.
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- W2048710746 doi "https://doi.org/10.1378/chest.06-2839" @default.
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