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• W2048715433 endingPage "65" @default.
• W2048715433 startingPage "54" @default.
• W2048715433 abstract "Objective To present guidelines for the analysis and presentation of clinical trials on prostate cancer. Methods Textbooks in statistics and oncology were searched for information, as were separate articles on the topic. Previously published advice was fused with own experience. Results Minimum key points are given for the sections: Introduction, Materials and Methods, Results, Discussion, and Summary. The importance of 1 primary question in any clinical trial is stressed. The value of a detailed presentation of the trial design, the patient population and the inclusion/exclusion criteria, the characterization of the disease, the treatment schedules, and toxicity is underlined. Application of various statistical methods for different endpoints is suggested. Maturity of data, time for publication, and avoidance of publication bias are discussed. Some common pitfalls in the statistical analyses of clinical results are indicated. The impact of prognostic factors, proper staging procedures, and secondary treatments on the interpretation of survival analysis is pointed out. A shift from the (mis-)use of the P value in favor of confidence intervals is strongly encouraged. The use of comparing the survival of responders versus nonresponders is to be abandoned. A few practical hints concerning the presentation are offered. The minimum of data that should be presented in absolute numbers is indicated. Also, the data that should be provided in both graphic and numeric format are exemplified. Examples of essential graphic illustrations are provided. The need for improvements in the design, analysis, and presentation of clinical trials is reemphasized. Finally, numerous references are listed. The article is addressed not only to authors and readers of clinical trials, but also to editors of medical journals. Conclusion The suggested guidelines may be useful in the analysis, presentation, and interpretation of clinical trials on prostate cancer. Moreover, compliance with these guidelines may facilitate comparisons with other similar trials and also, the incorporation of single studies into metaanalyses." @default.
• W2048715433 created "2016-06-24" @default.
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• W2048715433 creator A5046110130 @default.
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• W2048715433 date "1997-04-01" @default.
• W2048715433 modified "2023-10-14" @default.
• W2048715433 title "Analysis and presentation" @default.
• W2048715433 cites W128405409 @default.
• W2048715433 cites W1498668468 @default.
• W2048715433 cites W1571179146 @default.
• W2048715433 cites W1579641819 @default.
• W2048715433 cites W1922161603 @default.
• W2048715433 cites W1965352960 @default.
• W2048715433 cites W1968817382 @default.
• W2048715433 cites W1973367494 @default.
• W2048715433 cites W1977833499 @default.
• W2048715433 cites W1982578198 @default.
• W2048715433 cites W1985523305 @default.
• W2048715433 cites W1987760833 @default.
• W2048715433 cites W1990262669 @default.
• W2048715433 cites W1993398606 @default.
• W2048715433 cites W2007010240 @default.
• W2048715433 cites W2008777281 @default.
• W2048715433 cites W2010135964 @default.
• W2048715433 cites W2010476323 @default.
• W2048715433 cites W2012616356 @default.
• W2048715433 cites W2012947453 @default.
• W2048715433 cites W2013256551 @default.
• W2048715433 cites W2016526647 @default.
• W2048715433 cites W2020702724 @default.
• W2048715433 cites W2022396301 @default.
• W2048715433 cites W2026321407 @default.
• W2048715433 cites W2028269517 @default.
• W2048715433 cites W2030958316 @default.
• W2048715433 cites W2031088929 @default.
• W2048715433 cites W2031505013 @default.
• W2048715433 cites W2031890943 @default.
• W2048715433 cites W2034681918 @default.
• W2048715433 cites W2037887807 @default.
• W2048715433 cites W2038252730 @default.
• W2048715433 cites W2039002740 @default.
• W2048715433 cites W2039128844 @default.
• W2048715433 cites W2044763202 @default.
• W2048715433 cites W2055146603 @default.
• W2048715433 cites W2056590595 @default.
• W2048715433 cites W2057212716 @default.
• W2048715433 cites W2058223996 @default.
• W2048715433 cites W2069825350 @default.
• W2048715433 cites W2073140442 @default.
• W2048715433 cites W2074918076 @default.
• W2048715433 cites W2077715500 @default.
• W2048715433 cites W2078110114 @default.
• W2048715433 cites W2086481317 @default.
• W2048715433 cites W2099158992 @default.
• W2048715433 cites W2106051200 @default.
• W2048715433 cites W2110608811 @default.
• W2048715433 cites W2115397876 @default.
• W2048715433 cites W2120079339 @default.
• W2048715433 cites W2121361638 @default.
• W2048715433 cites W2132421073 @default.
• W2048715433 cites W2135444901 @default.
• W2048715433 cites W2136211460 @default.
• W2048715433 cites W2144504916 @default.
• W2048715433 cites W2147216906 @default.
• W2048715433 cites W2158922990 @default.
• W2048715433 cites W2167805334 @default.
• W2048715433 cites W2189078389 @default.
• W2048715433 cites W221956105 @default.
• W2048715433 cites W2284850045 @default.
• W2048715433 cites W2314635417 @default.
• W2048715433 cites W2397000251 @default.
• W2048715433 cites W2402753690 @default.
• W2048715433 cites W2404257121 @default.
• W2048715433 cites W2408151607 @default.
• W2048715433 cites W2409398082 @default.
• W2048715433 cites W2410734210 @default.
• W2048715433 cites W2412170257 @default.
• W2048715433 cites W2414951782 @default.
• W2048715433 cites W2418362738 @default.
• W2048715433 cites W2435165640 @default.
• W2048715433 cites W2465458076 @default.
• W2048715433 cites W2468696072 @default.
• W2048715433 cites W2471857435 @default.
• W2048715433 cites W2496614195 @default.
• W2048715433 cites W2796782673 @default.
• W2048715433 cites W3015748923 @default.
• W2048715433 cites W3022821183 @default.
• W2048715433 cites W3025885991 @default.
• W2048715433 cites W340060675 @default.
• W2048715433 cites W35572730 @default.
• W2048715433 cites W437641456 @default.
• W2048715433 cites W2000137303 @default.
• W2048715433 cites W2527243587 @default.
• W2048715433 doi "https://doi.org/10.1016/s0090-4295(99)80324-0" @default.
• W2048715433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9111615" @default.
• W2048715433 hasPublicationYear "1997" @default.

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