FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048718744> ?p ?o ?g. }

• W2048718744 endingPage "50" @default.
• W2048718744 startingPage "42" @default.
• W2048718744 abstract "Recent studies have explored the implication of melanin-concentrating hormone (MCH) in the process of vigilance states. The current experiments were carried out in mice lacking the MCH(1) receptor (-/-) and wild-type (WT) littermates, to assess the role of MCH(1) receptor in the regulation of sleep architecture, body temperature (BT) and locomotor activity (LMA) under normal condition and following a 1h restraint stress at lights onset. Under baseline conditions, MCH(1) (-/-) mice exhibited consistent changes in waking and sleeping time across the 24-h recording period. We found an increase in the amount of wakefulness (MCH(1) (-/-) 680.1 ± 15.3 min vs. WT, 601.9 ± 18.1, p<0.05) at the expense of total duration of non rapid eye movement (NREM) sleep (MCH(1) (-/-) 664.1 ± 13.9 min vs. WT 750.1 ± 18.5, p<0.05). Additionally, MCH(1) (-/-) mice had a higher mean basal body temperature (MCH(1) (-/-), 36.6 ± 0.1°C vs. WT, 36.0 ± 0.1°C, p<0.05), particularly during the light-resting period. Restraint stress resulted in an immediate increase in wakefulness with a concomitant reduction in NREM sleep and REM sleep in both genotypes, followed by a homeostatic rebound sleep. A concomitant long lasting increase in BT, independently of the behavioural state accompanied those changes in both genotypes. The elevated basal body temperature and reduction in NREM sleep time resulting from shorter NREM episode durations observed in MCH(1) (-/-) suggests that central MCH(1) receptor has a role in thermoregulation and presumably stabilization of NREM sleep." @default.
• W2048718744 created "2016-06-24" @default.
• W2048718744 creator A5024619102 @default.
• W2048718744 creator A5040568010 @default.
• W2048718744 creator A5050085256 @default.
• W2048718744 creator A5055066189 @default.
• W2048718744 creator A5064438468 @default.
• W2048718744 date "2011-03-01" @default.
• W2048718744 modified "2023-10-16" @default.
• W2048718744 title "Contribution of melanin-concentrating hormone (MCH1) receptor to thermoregulation and sleep stabilization: Evidence from MCH1 (−/−) mice" @default.
• W2048718744 cites W1481893565 @default.
• W2048718744 cites W1519232679 @default.
• W2048718744 cites W1523255158 @default.
• W2048718744 cites W1537142000 @default.
• W2048718744 cites W1579647545 @default.
• W2048718744 cites W1627229807 @default.
• W2048718744 cites W1793127045 @default.
• W2048718744 cites W1939585081 @default.
• W2048718744 cites W1968788710 @default.
• W2048718744 cites W1972887738 @default.
• W2048718744 cites W1978082185 @default.
• W2048718744 cites W1983627599 @default.
• W2048718744 cites W1993137505 @default.
• W2048718744 cites W1996709320 @default.
• W2048718744 cites W1999052502 @default.
• W2048718744 cites W2002293846 @default.
• W2048718744 cites W2007587250 @default.
• W2048718744 cites W2007831460 @default.
• W2048718744 cites W2022534400 @default.
• W2048718744 cites W2025670541 @default.
• W2048718744 cites W2027207893 @default.
• W2048718744 cites W2037277190 @default.
• W2048718744 cites W2040473331 @default.
• W2048718744 cites W2066503167 @default.
• W2048718744 cites W2077425962 @default.
• W2048718744 cites W2081593252 @default.
• W2048718744 cites W2081710585 @default.
• W2048718744 cites W2085867569 @default.
• W2048718744 cites W2089408029 @default.
• W2048718744 cites W2090627682 @default.
• W2048718744 cites W2102050521 @default.
• W2048718744 cites W2111031293 @default.
• W2048718744 cites W2115070641 @default.
• W2048718744 cites W2129268120 @default.
• W2048718744 cites W2160442886 @default.
• W2048718744 cites W2162007196 @default.
• W2048718744 cites W2166745166 @default.
• W2048718744 cites W2167591942 @default.
• W2048718744 cites W2359251903 @default.
• W2048718744 cites W4252265800 @default.
• W2048718744 doi "https://doi.org/10.1016/j.bbr.2010.11.019" @default.
• W2048718744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21074567" @default.
• W2048718744 hasPublicationYear "2011" @default.
• W2048718744 type Work @default.
• W2048718744 sameAs 2048718744 @default.
• W2048718744 citedByCount "25" @default.
• W2048718744 countsByYear W20487187442012 @default.
• W2048718744 countsByYear W20487187442013 @default.
• W2048718744 countsByYear W20487187442014 @default.
• W2048718744 countsByYear W20487187442015 @default.
• W2048718744 countsByYear W20487187442016 @default.
• W2048718744 countsByYear W20487187442017 @default.
• W2048718744 countsByYear W20487187442018 @default.
• W2048718744 countsByYear W20487187442020 @default.
• W2048718744 countsByYear W20487187442021 @default.
• W2048718744 countsByYear W20487187442022 @default.
• W2048718744 countsByYear W20487187442023 @default.
• W2048718744 crossrefType "journal-article" @default.
• W2048718744 hasAuthorship W2048718744A5024619102 @default.
• W2048718744 hasAuthorship W2048718744A5040568010 @default.
• W2048718744 hasAuthorship W2048718744A5050085256 @default.
• W2048718744 hasAuthorship W2048718744A5055066189 @default.
• W2048718744 hasAuthorship W2048718744A5064438468 @default.
• W2048718744 hasConcept C100564792 @default.
• W2048718744 hasConcept C110539466 @default.
• W2048718744 hasConcept C111919701 @default.
• W2048718744 hasConcept C118303440 @default.
• W2048718744 hasConcept C126322002 @default.
• W2048718744 hasConcept C134018914 @default.
• W2048718744 hasConcept C153050134 @default.
• W2048718744 hasConcept C15744967 @default.
• W2048718744 hasConcept C169760540 @default.
• W2048718744 hasConcept C170493617 @default.
• W2048718744 hasConcept C185592680 @default.
• W2048718744 hasConcept C192769605 @default.
• W2048718744 hasConcept C20566671 @default.
• W2048718744 hasConcept C2775841894 @default.
• W2048718744 hasConcept C2776632733 @default.
• W2048718744 hasConcept C2779213384 @default.
• W2048718744 hasConcept C2779320081 @default.
• W2048718744 hasConcept C41008148 @default.
• W2048718744 hasConcept C522805319 @default.
• W2048718744 hasConcept C71924100 @default.
• W2048718744 hasConcept C86803240 @default.
• W2048718744 hasConceptScore W2048718744C100564792 @default.
• W2048718744 hasConceptScore W2048718744C110539466 @default.
• W2048718744 hasConceptScore W2048718744C111919701 @default.
• W2048718744 hasConceptScore W2048718744C118303440 @default.

• next