Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048718807> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2048718807 endingPage "196" @default.
- W2048718807 startingPage "189" @default.
- W2048718807 abstract "Adipose tissue and adipocytes play a central role in the pathogenesis of metabolic diseases related to obesity. Size of fat cells depends on the balance of synthesis and mobilization of lipids and can undergo important variations throughout the life of the organism. These variations usually occur when storing and releasing lipids according to energy demand. In particular when confronted to severe food restriction, adipocyte releases its lipid content via a process called lipolysis. We propose a mathematical model that combines cell diameter distribution and lipolytic response to show that lipid release is a surface (radius squared) limited mechanism. Since this size-dependent rate affects the cell׳s shrinkage speed, we are able to predict the cell size distribution evolution when lipolysis is the only factor at work: such as during an important food restriction. Performing recurrent surgical biopsies on rats, we measured the evolution of adipose cell size distribution for the same individual throughout the duration of the food restriction protocol. We show that our microscopic model of size dependent lipid release can predict macroscopic size distribution evolution." @default.
- W2048718807 created "2016-06-24" @default.
- W2048718807 creator A5021381890 @default.
- W2048718807 creator A5050129805 @default.
- W2048718807 creator A5088971388 @default.
- W2048718807 date "2015-01-01" @default.
- W2048718807 modified "2023-10-18" @default.
- W2048718807 title "Model of adipose tissue cellularity dynamics during food restriction" @default.
- W2048718807 cites W1558846251 @default.
- W2048718807 cites W1777045282 @default.
- W2048718807 cites W1900340925 @default.
- W2048718807 cites W1922643401 @default.
- W2048718807 cites W1940950287 @default.
- W2048718807 cites W1975255696 @default.
- W2048718807 cites W1983210369 @default.
- W2048718807 cites W1986634288 @default.
- W2048718807 cites W1987701104 @default.
- W2048718807 cites W1993959456 @default.
- W2048718807 cites W2001500646 @default.
- W2048718807 cites W2006596211 @default.
- W2048718807 cites W2008644748 @default.
- W2048718807 cites W2016581462 @default.
- W2048718807 cites W2017676683 @default.
- W2048718807 cites W2023218469 @default.
- W2048718807 cites W2036139926 @default.
- W2048718807 cites W2038961236 @default.
- W2048718807 cites W2050679442 @default.
- W2048718807 cites W2056082588 @default.
- W2048718807 cites W2073789869 @default.
- W2048718807 cites W2081458019 @default.
- W2048718807 cites W2082835899 @default.
- W2048718807 cites W2097170770 @default.
- W2048718807 cites W2107940713 @default.
- W2048718807 cites W2117188422 @default.
- W2048718807 cites W2139608294 @default.
- W2048718807 cites W2158196600 @default.
- W2048718807 cites W2181312359 @default.
- W2048718807 cites W2227126326 @default.
- W2048718807 doi "https://doi.org/10.1016/j.jtbi.2014.08.046" @default.
- W2048718807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25196549" @default.
- W2048718807 hasPublicationYear "2015" @default.
- W2048718807 type Work @default.
- W2048718807 sameAs 2048718807 @default.
- W2048718807 citedByCount "9" @default.
- W2048718807 countsByYear W20487188072015 @default.
- W2048718807 countsByYear W20487188072016 @default.
- W2048718807 countsByYear W20487188072020 @default.
- W2048718807 countsByYear W20487188072021 @default.
- W2048718807 crossrefType "journal-article" @default.
- W2048718807 hasAuthorship W2048718807A5021381890 @default.
- W2048718807 hasAuthorship W2048718807A5050129805 @default.
- W2048718807 hasAuthorship W2048718807A5088971388 @default.
- W2048718807 hasConcept C126322002 @default.
- W2048718807 hasConcept C134018914 @default.
- W2048718807 hasConcept C140985366 @default.
- W2048718807 hasConcept C1491633281 @default.
- W2048718807 hasConcept C171089720 @default.
- W2048718807 hasConcept C185592680 @default.
- W2048718807 hasConcept C2776175234 @default.
- W2048718807 hasConcept C3017597547 @default.
- W2048718807 hasConcept C55493867 @default.
- W2048718807 hasConcept C71924100 @default.
- W2048718807 hasConcept C86803240 @default.
- W2048718807 hasConcept C95444343 @default.
- W2048718807 hasConceptScore W2048718807C126322002 @default.
- W2048718807 hasConceptScore W2048718807C134018914 @default.
- W2048718807 hasConceptScore W2048718807C140985366 @default.
- W2048718807 hasConceptScore W2048718807C1491633281 @default.
- W2048718807 hasConceptScore W2048718807C171089720 @default.
- W2048718807 hasConceptScore W2048718807C185592680 @default.
- W2048718807 hasConceptScore W2048718807C2776175234 @default.
- W2048718807 hasConceptScore W2048718807C3017597547 @default.
- W2048718807 hasConceptScore W2048718807C55493867 @default.
- W2048718807 hasConceptScore W2048718807C71924100 @default.
- W2048718807 hasConceptScore W2048718807C86803240 @default.
- W2048718807 hasConceptScore W2048718807C95444343 @default.
- W2048718807 hasLocation W20487188071 @default.
- W2048718807 hasLocation W20487188072 @default.
- W2048718807 hasLocation W20487188073 @default.
- W2048718807 hasLocation W20487188074 @default.
- W2048718807 hasOpenAccess W2048718807 @default.
- W2048718807 hasPrimaryLocation W20487188071 @default.
- W2048718807 hasRelatedWork W141125801 @default.
- W2048718807 hasRelatedWork W1592691368 @default.
- W2048718807 hasRelatedWork W1996584884 @default.
- W2048718807 hasRelatedWork W2018864477 @default.
- W2048718807 hasRelatedWork W2031466315 @default.
- W2048718807 hasRelatedWork W2046890775 @default.
- W2048718807 hasRelatedWork W2048359366 @default.
- W2048718807 hasRelatedWork W2059693088 @default.
- W2048718807 hasRelatedWork W2125103862 @default.
- W2048718807 hasRelatedWork W2132141669 @default.
- W2048718807 hasVolume "364" @default.
- W2048718807 isParatext "false" @default.
- W2048718807 isRetracted "false" @default.
- W2048718807 magId "2048718807" @default.
- W2048718807 workType "article" @default.