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• W2048774650 abstract "Bioassay guided isolation of an antibacterial extract prepared from the fermentation broth of a Micromonospora sp. P1068 led to the isolation of eight compounds identified as (3R) 3,4′,7-trihydroxy-isoflavanone (1), 3-hydroxydehydrodaidzein, daidzein (2), 3-methyl-1H-indole-2-carboxylic acid (3), 1H-indole-3-carboxaldehyde (4), 3-(p-hydroxyphenyl)-N-methylpropionamide, N-methylphloretamide (5), phenyl acetic acid (6), 2-hydroxy phenyl acetic acid (7) and 4-hydroxy-5-methoxy-benzoic acid (8). Compounds 1 and 5 were found to be novel chemical entities while 3 was isolated from a natural source for the first time. All compounds were evaluated for their antimicrobial activities against a panel of clinically significant microorganisms. Compound 4 was active against Staphylococcus aureus (MIC, 32 µg/ml), Enterococcus faecium (MIC, 32 µg/ml) and Escherichia coli (MIC, 64 µg/ml)." @default.
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• W2048774650 date "2005-10-01" @default.
• W2048774650 modified "2023-09-29" @default.
• W2048774650 title "Isolation of three new naturally occurring compounds from the culture of<i>Micromonospora</i>sp. P1068" @default.
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• W2048774650 doi "https://doi.org/10.1080/14786410412331272040" @default.
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