Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048776474> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2048776474 endingPage "1447" @default.
- W2048776474 startingPage "1441" @default.
- W2048776474 abstract "Abstract Development of the lip and palate involves a complex series of events that are frequently disturbed resulting in the congenital anomalies cleft lip and cleft palate. Van der Woude syndrome (VWS) is an autosomal dominant disorder that is characterised by cleft lip, cleft palate, lower lip pits, and hypodontia. VWS arises as the result of mutations in the gene encoding interferon regulatory factor 6 (IRF6). To provide insights into the role of IRF6 during embryogenesis, we have analysed the expression of this molecule during mouse and chick facial development. Irf6 was expressed in the ectoderm covering the facial processes during their fusion to form the upper lip and primary palate in both mouse and chick. However, while Irf6 was expressed in the medial edge epithelia of the developing secondary palate of the mouse, which fuses as in man, Irf6 was not expressed in the medial edge epithelia of the naturally cleft chick secondary palate. Similarly, Irf6 was found to be down‐regulated in the medial edge epithelia of transforming growth factor beta3‐null mice, which also exhibit cleft palate. Together, these results support a role for IRF6 during the fusion events that occur during development of the lip and palate. Developmental Dynamics 235:1441–1447, 2006. © 2005 Wiley‐Liss, Inc." @default.
- W2048776474 created "2016-06-24" @default.
- W2048776474 creator A5007146462 @default.
- W2048776474 creator A5050198479 @default.
- W2048776474 creator A5071759530 @default.
- W2048776474 creator A5074772421 @default.
- W2048776474 date "2005-10-21" @default.
- W2048776474 modified "2023-09-29" @default.
- W2048776474 title "Developmental expression analysis of the mouse and chick orthologues ofIRF6: The gene mutated in Van der Woude syndrome" @default.
- W2048776474 cites W1521875254 @default.
- W2048776474 cites W1572873372 @default.
- W2048776474 cites W1858922792 @default.
- W2048776474 cites W1889850148 @default.
- W2048776474 cites W1930635713 @default.
- W2048776474 cites W1970686467 @default.
- W2048776474 cites W1977025966 @default.
- W2048776474 cites W1981888346 @default.
- W2048776474 cites W1983969951 @default.
- W2048776474 cites W1993000387 @default.
- W2048776474 cites W1998186185 @default.
- W2048776474 cites W2021640816 @default.
- W2048776474 cites W2028495167 @default.
- W2048776474 cites W2035757354 @default.
- W2048776474 cites W2043545171 @default.
- W2048776474 cites W2064050439 @default.
- W2048776474 cites W2065333356 @default.
- W2048776474 cites W2085601531 @default.
- W2048776474 cites W2094165314 @default.
- W2048776474 cites W2108399976 @default.
- W2048776474 cites W2118526247 @default.
- W2048776474 cites W2131036795 @default.
- W2048776474 cites W2155935761 @default.
- W2048776474 cites W3212157965 @default.
- W2048776474 cites W4212811418 @default.
- W2048776474 cites W4255985027 @default.
- W2048776474 doi "https://doi.org/10.1002/dvdy.20598" @default.
- W2048776474 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16245336" @default.
- W2048776474 hasPublicationYear "2005" @default.
- W2048776474 type Work @default.
- W2048776474 sameAs 2048776474 @default.
- W2048776474 citedByCount "82" @default.
- W2048776474 countsByYear W20487764742012 @default.
- W2048776474 countsByYear W20487764742013 @default.
- W2048776474 countsByYear W20487764742014 @default.
- W2048776474 countsByYear W20487764742015 @default.
- W2048776474 countsByYear W20487764742016 @default.
- W2048776474 countsByYear W20487764742017 @default.
- W2048776474 countsByYear W20487764742018 @default.
- W2048776474 countsByYear W20487764742019 @default.
- W2048776474 countsByYear W20487764742020 @default.
- W2048776474 countsByYear W20487764742021 @default.
- W2048776474 countsByYear W20487764742022 @default.
- W2048776474 countsByYear W20487764742023 @default.
- W2048776474 crossrefType "journal-article" @default.
- W2048776474 hasAuthorship W2048776474A5007146462 @default.
- W2048776474 hasAuthorship W2048776474A5050198479 @default.
- W2048776474 hasAuthorship W2048776474A5071759530 @default.
- W2048776474 hasAuthorship W2048776474A5074772421 @default.
- W2048776474 hasConcept C104317684 @default.
- W2048776474 hasConcept C105702510 @default.
- W2048776474 hasConcept C2779385247 @default.
- W2048776474 hasConcept C2780216207 @default.
- W2048776474 hasConcept C29694066 @default.
- W2048776474 hasConcept C54355233 @default.
- W2048776474 hasConcept C71924100 @default.
- W2048776474 hasConcept C86803240 @default.
- W2048776474 hasConcept C95444343 @default.
- W2048776474 hasConceptScore W2048776474C104317684 @default.
- W2048776474 hasConceptScore W2048776474C105702510 @default.
- W2048776474 hasConceptScore W2048776474C2779385247 @default.
- W2048776474 hasConceptScore W2048776474C2780216207 @default.
- W2048776474 hasConceptScore W2048776474C29694066 @default.
- W2048776474 hasConceptScore W2048776474C54355233 @default.
- W2048776474 hasConceptScore W2048776474C71924100 @default.
- W2048776474 hasConceptScore W2048776474C86803240 @default.
- W2048776474 hasConceptScore W2048776474C95444343 @default.
- W2048776474 hasIssue "5" @default.
- W2048776474 hasLocation W20487764741 @default.
- W2048776474 hasLocation W20487764742 @default.
- W2048776474 hasOpenAccess W2048776474 @default.
- W2048776474 hasPrimaryLocation W20487764741 @default.
- W2048776474 hasRelatedWork W1991523530 @default.
- W2048776474 hasRelatedWork W2002128513 @default.
- W2048776474 hasRelatedWork W2009966535 @default.
- W2048776474 hasRelatedWork W2020824267 @default.
- W2048776474 hasRelatedWork W2031436818 @default.
- W2048776474 hasRelatedWork W2057739827 @default.
- W2048776474 hasRelatedWork W2075354549 @default.
- W2048776474 hasRelatedWork W2088063203 @default.
- W2048776474 hasRelatedWork W2171277769 @default.
- W2048776474 hasRelatedWork W2092874662 @default.
- W2048776474 hasVolume "235" @default.
- W2048776474 isParatext "false" @default.
- W2048776474 isRetracted "false" @default.
- W2048776474 magId "2048776474" @default.
- W2048776474 workType "article" @default.