FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048791806> ?p ?o ?g. }

• W2048791806 endingPage "220" @default.
• W2048791806 startingPage "215" @default.
• W2048791806 abstract "We assayed various brain regions for levels of monoamines and their metabolites throughout the hibernation cycle of the golden-mantled ground squirrel Spermophilus lateralis. The tissue concentrations of serotonin, dopamine, norepinephrine and their metabolites were determined in the parietal cortex, striatum, midbrain, hippocampus, hypothalamus, and pons. Telencephalic regions exhibited the most significant variations in biogenic amine content. Cortical serotonin (5-HT) levels increased significantly at entrance (P < 0.0001) relative to other period of the hibernation cycle, suggesting a role for 5-HT in the initiation of hibernation. Among striatal dopamine (DA) metabolites, 3-methoxytyramine was detectable only during euthermia and arousal; from entrance through arousal, homovanillic acid (HVA) levels were half that found during euthermia (P = 0.0001); and dihydroxyphenylacetic acid (DOPAC) levels increased during day 1 of hibernation (P < 0.0005). Midbrain DA (P = 0.0295) and hippocampal HVA (P = 0.0194) levels also changed significantly across the hibernation bout. The absence of a consistent change in any monoamine or metabolite throughout the brain precludes the possibility of preferential temperature-dependent impairment of an enzyme involved in biogenic amine synthesis or degradation and suggests that the levels observed reflect changes in neural activity specific to each brain region. Together with previous studies of brain 2-deoxyglucose uptake throughout the hibernation cycle, these data indicate that a transient change in afferent monoaminergic metabolism and neurotransmission in the forebrain is a necessary component for the entrance to hibernation." @default.
• W2048791806 created "2016-06-24" @default.
• W2048791806 creator A5015921374 @default.
• W2048791806 creator A5032309111 @default.
• W2048791806 creator A5036642361 @default.
• W2048791806 creator A5069587559 @default.
• W2048791806 creator A5080945426 @default.
• W2048791806 date "1991-11-01" @default.
• W2048791806 modified "2023-10-18" @default.
• W2048791806 title "Regional changes in central monoamine and metabolite levels during the hibernation cycle in the golden-mantled ground squirrel" @default.
• W2048791806 cites W1486374042 @default.
• W2048791806 cites W1837333360 @default.
• W2048791806 cites W1978494010 @default.
• W2048791806 cites W1992138801 @default.
• W2048791806 cites W2023459330 @default.
• W2048791806 cites W2031510060 @default.
• W2048791806 cites W2036907620 @default.
• W2048791806 cites W2045400278 @default.
• W2048791806 cites W2056894155 @default.
• W2048791806 cites W2089374334 @default.
• W2048791806 cites W2106207347 @default.
• W2048791806 cites W2464100468 @default.
• W2048791806 doi "https://doi.org/10.1016/0006-8993(91)91536-a" @default.
• W2048791806 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1786534" @default.
• W2048791806 hasPublicationYear "1991" @default.
• W2048791806 type Work @default.
• W2048791806 sameAs 2048791806 @default.
• W2048791806 citedByCount "19" @default.
• W2048791806 countsByYear W20487918062014 @default.
• W2048791806 countsByYear W20487918062015 @default.
• W2048791806 countsByYear W20487918062017 @default.
• W2048791806 countsByYear W20487918062018 @default.
• W2048791806 countsByYear W20487918062022 @default.
• W2048791806 crossrefType "journal-article" @default.
• W2048791806 hasAuthorship W2048791806A5015921374 @default.
• W2048791806 hasAuthorship W2048791806A5032309111 @default.
• W2048791806 hasAuthorship W2048791806A5036642361 @default.
• W2048791806 hasAuthorship W2048791806A5069587559 @default.
• W2048791806 hasAuthorship W2048791806A5080945426 @default.
• W2048791806 hasConcept C100564792 @default.
• W2048791806 hasConcept C11413529 @default.
• W2048791806 hasConcept C119865680 @default.
• W2048791806 hasConcept C126322002 @default.
• W2048791806 hasConcept C134018914 @default.
• W2048791806 hasConcept C170493617 @default.
• W2048791806 hasConcept C185592680 @default.
• W2048791806 hasConcept C187714386 @default.
• W2048791806 hasConcept C2775841634 @default.
• W2048791806 hasConcept C2775864247 @default.
• W2048791806 hasConcept C2776219046 @default.
• W2048791806 hasConcept C2778377861 @default.
• W2048791806 hasConcept C2780588931 @default.
• W2048791806 hasConcept C41008148 @default.
• W2048791806 hasConcept C42251903 @default.
• W2048791806 hasConcept C48103436 @default.
• W2048791806 hasConcept C513476851 @default.
• W2048791806 hasConcept C529278444 @default.
• W2048791806 hasConcept C552161191 @default.
• W2048791806 hasConcept C71924100 @default.
• W2048791806 hasConcept C86803240 @default.
• W2048791806 hasConceptScore W2048791806C100564792 @default.
• W2048791806 hasConceptScore W2048791806C11413529 @default.
• W2048791806 hasConceptScore W2048791806C119865680 @default.
• W2048791806 hasConceptScore W2048791806C126322002 @default.
• W2048791806 hasConceptScore W2048791806C134018914 @default.
• W2048791806 hasConceptScore W2048791806C170493617 @default.
• W2048791806 hasConceptScore W2048791806C185592680 @default.
• W2048791806 hasConceptScore W2048791806C187714386 @default.
• W2048791806 hasConceptScore W2048791806C2775841634 @default.
• W2048791806 hasConceptScore W2048791806C2775864247 @default.
• W2048791806 hasConceptScore W2048791806C2776219046 @default.
• W2048791806 hasConceptScore W2048791806C2778377861 @default.
• W2048791806 hasConceptScore W2048791806C2780588931 @default.
• W2048791806 hasConceptScore W2048791806C41008148 @default.
• W2048791806 hasConceptScore W2048791806C42251903 @default.
• W2048791806 hasConceptScore W2048791806C48103436 @default.
• W2048791806 hasConceptScore W2048791806C513476851 @default.
• W2048791806 hasConceptScore W2048791806C529278444 @default.
• W2048791806 hasConceptScore W2048791806C552161191 @default.
• W2048791806 hasConceptScore W2048791806C71924100 @default.
• W2048791806 hasConceptScore W2048791806C86803240 @default.
• W2048791806 hasIssue "1-2" @default.
• W2048791806 hasLocation W20487918061 @default.
• W2048791806 hasLocation W20487918062 @default.
• W2048791806 hasOpenAccess W2048791806 @default.
• W2048791806 hasPrimaryLocation W20487918061 @default.
• W2048791806 hasRelatedWork W1970563837 @default.
• W2048791806 hasRelatedWork W2014789471 @default.
• W2048791806 hasRelatedWork W2018972664 @default.
• W2048791806 hasRelatedWork W2048791806 @default.
• W2048791806 hasRelatedWork W2082644207 @default.
• W2048791806 hasRelatedWork W2091373293 @default.
• W2048791806 hasRelatedWork W2110116147 @default.
• W2048791806 hasRelatedWork W2112684472 @default.
• W2048791806 hasRelatedWork W2171454471 @default.
• W2048791806 hasRelatedWork W71079269 @default.
• W2048791806 hasVolume "563" @default.
• W2048791806 isParatext "false" @default.

• next