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- W2048795044 abstract "It is well known that psychiatric patients have an increased incidence of chronic medical problems with advancing age including hypertension and obesity. As part of an ongoing study we evaluated the efficacy of different classes of antihypertensive drugs currently in use for treating hypertension in the population. Patients were selected from the inpatient units at ECHC based on medical history as well as data reviewed for weekly blood pressure readings over the last 6 months that met prior criteria for elevated Blood Pressure. Fifty-three patients met the criteria, compromising 28 females and 25 males. The mean age for the females was 59 years and males 49 years. The main body mass index was 33 for females and 30 for males. Ninety percent of the patients had Schizophrenia as the primary diagnosis. Combination therapy was used by 84 percent of the patients and the most common combination was ace/diuretic (75%), the least common single drug was angiotensin receptor blocker (3.7%). Seven patients (15%) were on ace/beta blocker combination. The standard psychotropic drugs used in various combinations were zyprexa, cogentin, haldol and risperdal. Compliance was assured by daily observation and monitoring. The average blood pressure, post treatment for the females was 138/88 and for males 140/84. Review of the data showed that the most effective lowering of the blood presure was obtained with ace/diuretics as a combination therapy, and second most effective with diuretic as mono therapy. Our data suggest that the most cost effective control of blood pressure was obtained with diuretics as a single agent and ace/diuretics as combination therapy in this chronic and persistent mentally ill population. Further studies would help to validate this observation." @default.
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- W2048795044 date "2002-04-01" @default.
- W2048795044 modified "2023-09-27" @default.
- W2048795044 title "The efficacy of antihypertensive medications in a psychiatric population" @default.
- W2048795044 doi "https://doi.org/10.1016/s0895-7061(02)02435-4" @default.
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