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- W2048799387 abstract "Kidneys from 20 dogs were dissected into cortical and medullary components and analysed for acid mucopolysaccharide content. Heparitin sulfate accounted for approximately 80% of cortical acid mucopolysaccharide, 10% was chondroitin sulfate B, and 10% was low molecular weight hyaluronic acid. Medullary tissue exhibited a 4- to 5-fold higher concentration of acid mucopolysaccharide than did cortical tissue, and the dominant compound was moderately highly polymerized hyaluronic acid. While chondroitin sulfates A and (or) C were not detected in this study, the presence of minor amounts of these substances could not be excluded. A model experiment indicated that hyaluronic acid retards sodium diffusion, apparently due to its viscous properties rather than its electronegativity." @default.
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- W2048799387 date "1968-09-01" @default.
- W2048799387 modified "2023-10-12" @default.
- W2048799387 title "Regional distribution of acid mucopolysaccharides in the kidney" @default.
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- W2048799387 doi "https://doi.org/10.1172/jci105898" @default.
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