FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048805624> ?p ?o ?g. }

• W2048805624 endingPage "90" @default.
• W2048805624 startingPage "83" @default.
• W2048805624 abstract "Insulin-like growth factor-I (IGF-I) is elevated in human fibrotic lung diseases and in animal models of pulmonary fibrosis, implicating IGF-I in the pathogenesis of fibrotic lung disease. We questioned whether IGF-I protein levels were enhanced in fibroproliferative acute respiratory distress syndrome (FP-ARDS). Serial lung tissue sections from a biopsy database were immunohistochemically stained for IGF-I, IGF-I receptor, CD68, α-smooth muscle actin, collagens I and III, and proliferating cell nuclear antigen. Our results show enhanced staining of IGF-I and IGF-I receptor, collagens I and III, smooth muscle actin, CD68, and proliferating cell nuclear antigen in FP-ARDS compared with control lung sections. In FP-ARDS specimens, prominent staining of IGF-I and IGF-I receptor was seen in alveolar and interstitial macrophages as well as in a variety of mesenchymal cells. There was a correlation between IGF-I staining and CD68-positive cells, suggesting macrophages as a potential source of the IGF-I protein present in lungs. IGF-I also correlated with enhanced collagen I, collagen III, and proliferating cell nuclear antigen immunoreactivity, suggesting that IGF-I may play a role in the extracellular matrix protein deposition and cellular proliferation seen in the lungs of individuals with FP-ARDS. Our results indicate that IGF-I is increased in FP-ARDS and may be an important mediator in the progression of acute lung injury to FP-ARDS." @default.
• W2048805624 created "2016-06-24" @default.
• W2048805624 creator A5015363285 @default.
• W2048805624 creator A5056799168 @default.
• W2048805624 creator A5065782582 @default.
• W2048805624 creator A5067794783 @default.
• W2048805624 creator A5075669962 @default.
• W2048805624 date "2003-01-01" @default.
• W2048805624 modified "2023-10-16" @default.
• W2048805624 title "Localization of Insulin-like Growth Factor-I in Lung Tissues of Patients with Fibroproliferative Acute Respiratory Distress Syndrome" @default.
• W2048805624 cites W1516018176 @default.
• W2048805624 cites W1931526140 @default.
• W2048805624 cites W1970516412 @default.
• W2048805624 cites W2007794555 @default.
• W2048805624 cites W2011347121 @default.
• W2048805624 cites W2012306213 @default.
• W2048805624 cites W2020753889 @default.
• W2048805624 cites W2024503266 @default.
• W2048805624 cites W2025230591 @default.
• W2048805624 cites W2034287052 @default.
• W2048805624 cites W2037459166 @default.
• W2048805624 cites W2056240226 @default.
• W2048805624 cites W2083755620 @default.
• W2048805624 cites W2084320631 @default.
• W2048805624 cites W2084745363 @default.
• W2048805624 cites W2084787741 @default.
• W2048805624 cites W2087713324 @default.
• W2048805624 cites W2088081374 @default.
• W2048805624 cites W2092644867 @default.
• W2048805624 cites W2124870373 @default.
• W2048805624 cites W2128743400 @default.
• W2048805624 cites W2133096187 @default.
• W2048805624 cites W2137800135 @default.
• W2048805624 cites W2153354364 @default.
• W2048805624 cites W2185858582 @default.
• W2048805624 cites W4229683547 @default.
• W2048805624 cites W4294658238 @default.
• W2048805624 cites W92841504 @default.
• W2048805624 doi "https://doi.org/10.1164/rccm.2201012" @default.
• W2048805624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12502480" @default.
• W2048805624 hasPublicationYear "2003" @default.
• W2048805624 type Work @default.
• W2048805624 sameAs 2048805624 @default.
• W2048805624 citedByCount "68" @default.
• W2048805624 countsByYear W20488056242012 @default.
• W2048805624 countsByYear W20488056242013 @default.
• W2048805624 countsByYear W20488056242014 @default.
• W2048805624 countsByYear W20488056242015 @default.
• W2048805624 countsByYear W20488056242016 @default.
• W2048805624 countsByYear W20488056242017 @default.
• W2048805624 countsByYear W20488056242018 @default.
• W2048805624 countsByYear W20488056242020 @default.
• W2048805624 countsByYear W20488056242021 @default.
• W2048805624 countsByYear W20488056242022 @default.
• W2048805624 countsByYear W20488056242023 @default.
• W2048805624 crossrefType "journal-article" @default.
• W2048805624 hasAuthorship W2048805624A5015363285 @default.
• W2048805624 hasAuthorship W2048805624A5056799168 @default.
• W2048805624 hasAuthorship W2048805624A5065782582 @default.
• W2048805624 hasAuthorship W2048805624A5067794783 @default.
• W2048805624 hasAuthorship W2048805624A5075669962 @default.
• W2048805624 hasConcept C126322002 @default.
• W2048805624 hasConcept C142724271 @default.
• W2048805624 hasConcept C170493617 @default.
• W2048805624 hasConcept C204232928 @default.
• W2048805624 hasConcept C2775960820 @default.
• W2048805624 hasConcept C2776348555 @default.
• W2048805624 hasConcept C2776460901 @default.
• W2048805624 hasConcept C2777714996 @default.
• W2048805624 hasConcept C2780559512 @default.
• W2048805624 hasConcept C2780689927 @default.
• W2048805624 hasConcept C2781244666 @default.
• W2048805624 hasConcept C502942594 @default.
• W2048805624 hasConcept C71924100 @default.
• W2048805624 hasConceptScore W2048805624C126322002 @default.
• W2048805624 hasConceptScore W2048805624C142724271 @default.
• W2048805624 hasConceptScore W2048805624C170493617 @default.
• W2048805624 hasConceptScore W2048805624C204232928 @default.
• W2048805624 hasConceptScore W2048805624C2775960820 @default.
• W2048805624 hasConceptScore W2048805624C2776348555 @default.
• W2048805624 hasConceptScore W2048805624C2776460901 @default.
• W2048805624 hasConceptScore W2048805624C2777714996 @default.
• W2048805624 hasConceptScore W2048805624C2780559512 @default.
• W2048805624 hasConceptScore W2048805624C2780689927 @default.
• W2048805624 hasConceptScore W2048805624C2781244666 @default.
• W2048805624 hasConceptScore W2048805624C502942594 @default.
• W2048805624 hasConceptScore W2048805624C71924100 @default.
• W2048805624 hasIssue "1" @default.
• W2048805624 hasLocation W20488056241 @default.
• W2048805624 hasLocation W20488056242 @default.
• W2048805624 hasOpenAccess W2048805624 @default.
• W2048805624 hasPrimaryLocation W20488056241 @default.
• W2048805624 hasRelatedWork W2014231481 @default.
• W2048805624 hasRelatedWork W2058160713 @default.
• W2048805624 hasRelatedWork W2099817208 @default.
• W2048805624 hasRelatedWork W2119436088 @default.
• W2048805624 hasRelatedWork W2121592873 @default.
• W2048805624 hasRelatedWork W2130733926 @default.

• next