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- W2048852058 abstract "Abstract Methomyl analogues were synthesized by substituting alkyl moieties (C 2 -C 21 ) in the place of the carbamic methyl. They were assayed on mitochondria isolated from male sterile (F 7 T) and male fertile (F 7 N) maize. They had no action on F 7 N mitochondria. The heptadecyl (C 17 ) and heneicosanyl (C 21 ) derivatives had no conspicuous effect on F 7 T mitochondria. By contrast, the ethyl, propyl, butyl, nonyl, tridecyl (C 13 ) and pentadecyl (C 15 ) derivatives had the same type of activity as Methomyl on F 7 T mitochondria, namely stimulation of NADH oxidation and inhibition of malate oxidation. Moreover, the concentration at which they were maximally effective decreased from 10 mM (Methomyl) to 3 μM (tridecyl derivative); hence, the latter compound has a biological activity which is nearly the same as that of Helminthosporium maydis toxin." @default.
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- W2048852058 date "1987-01-01" @default.
- W2048852058 modified "2023-09-26" @default.
- W2048852058 title "Methomyl analogues with increased biological activity towards F7T maize mitochondria" @default.
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- W2048852058 doi "https://doi.org/10.1016/s0031-9422(00)81726-4" @default.
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