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• W2048894489 abstract "Carbohydrate porphyrin conjugates (CPCs) have gained attention for their ability to serve as water soluble catalysts and therapeutics for photodynamic therapy (PDT). However, the synthesis of these compounds continues to be a significant challenge. In this Letter we detail the direct synthesis of a series of glycosylated porphyrins prepared directly from Zn(II) 5,15-[p-(ethynyl)-diphenyl] or Zn(II) 5,10,15,20-[p-(ethynyl)-diphenyl] porphyrins and per-O-acetylated sugar azides using copper catalyzed 1,3-dipolarcycloaddition reactions. The highest yields were achieved using a copper (II) catalyst reduced in situ, and we were able to achieve average yields greater than 90% per cycloaddition reaction." @default.
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• W2048894489 date "2015-01-01" @default.
• W2048894489 modified "2023-10-18" @default.
• W2048894489 title "Synthesis of glycosylated zinc (II) 5,15-diphenylporphyrin and zinc (II) 5,10,15,20-tetraphenylporphyrin analogs using Cu-catalyzed azide-alkyne 1,3-dipolar cycloaddition reactions" @default.
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• W2048894489 doi "https://doi.org/10.1016/j.tetlet.2014.10.117" @default.
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