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- W2048898072 abstract "A history of acute otitis media (AOM) often precedes development of otitis media with effusion (OME); where that history pre-dates the first birthday an increased risk has been demonstrated previously. The possibility of establishing a critical period of susceptibility to the priming attack of AOM is explored using a large national database. The complete GP histories of 7510 children born in the year beginning October 1989 and followed until their fifth year of life, within practices representative of England and Wales, permit examination of the following risk factors: history of asthma, eczema and hayfever; type and timing of all middle-ear-related conditions; upper respiratory tract infections; reported snoring; sex. The following risk factors were confirmed: sex, atopy (in particular hayfever), nose, chest and throat infections (particularly chest), and reported snoring. Age of first attack of AOM was the strongest indicator of subsequent OME. Risk decreased with increased age. Different age groups were examined in 3-month bands and a critical period could be detected covering the first 9 months of life. Risk of subsequent OME varied slightly by season of first AOM, particularly within the critical period. Children born in spring appeared to be at highest risk." @default.
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- W2048898072 date "1998-06-01" @default.
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- W2048898072 title "Do seasonal priming effects in the first months of life influence development of middle ear disease?" @default.
- W2048898072 doi "https://doi.org/10.1046/j.1365-2273.1998.0137g.x" @default.
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