FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048960987> ?p ?o ?g. }

• W2048960987 endingPage "124" @default.
• W2048960987 startingPage "115" @default.
• W2048960987 abstract "Genetic (genomic) and environmental (non-genetic) factors are the two main aspects that determine phenotype. Although there has long been a tendency to separate them (nature versus nurture), in essentially all traits (diseases) besides those secondary to trauma, both the genetic and environmental factors interact to develop the phenotype (nature and nurture). Traits (diseases) can be divided into two broad categories based on their genetic components pattern of transmission. The first category include so called simple (Mendelian) traits. The second category includes genetically complex traits. These are more common than Mendelian traits. They do not follow a clear pattern of inheritance, but they tend to run in families. Relatives of an affected individual or one who has the trait have an increased risk of developing the disease and or having the trait. The genetic determinants of such traits are difficult to identify since the trait or disease results from a set of genetic polymorphisms that may be common within the population, both affected and non-affected. The interplay of these genetic polymorphisms at different loci with environmental factors leads to the manifestation of such complex traits. Some approaches to analyzing complex traits using external apical root resorption as an example are reviewed. Genetic (genomic) and environmental (non-genetic) factors are the two main aspects that determine phenotype. Although there has long been a tendency to separate them (nature versus nurture), in essentially all traits (diseases) besides those secondary to trauma, both the genetic and environmental factors interact to develop the phenotype (nature and nurture). Traits (diseases) can be divided into two broad categories based on their genetic components pattern of transmission. The first category include so called simple (Mendelian) traits. The second category includes genetically complex traits. These are more common than Mendelian traits. They do not follow a clear pattern of inheritance, but they tend to run in families. Relatives of an affected individual or one who has the trait have an increased risk of developing the disease and or having the trait. The genetic determinants of such traits are difficult to identify since the trait or disease results from a set of genetic polymorphisms that may be common within the population, both affected and non-affected. The interplay of these genetic polymorphisms at different loci with environmental factors leads to the manifestation of such complex traits. Some approaches to analyzing complex traits using external apical root resorption as an example are reviewed." @default.
• W2048960987 created "2016-06-24" @default.
• W2048960987 creator A5035946946 @default.
• W2048960987 creator A5066911732 @default.
• W2048960987 date "2008-06-01" @default.
• W2048960987 modified "2023-09-26" @default.
• W2048960987 title "Investigation of Genetic Factors Affecting Complex Traits Using External Apical Root Resorption as a Model" @default.
• W2048960987 cites W1971720206 @default.
• W2048960987 cites W1977886864 @default.
• W2048960987 cites W1982024994 @default.
• W2048960987 cites W2000100005 @default.
• W2048960987 cites W2004734657 @default.
• W2048960987 cites W2034422377 @default.
• W2048960987 cites W2036103009 @default.
• W2048960987 cites W2053938293 @default.
• W2048960987 cites W2059750800 @default.
• W2048960987 cites W2061527703 @default.
• W2048960987 cites W2068427340 @default.
• W2048960987 cites W2087635175 @default.
• W2048960987 cites W2112922155 @default.
• W2048960987 cites W2142877684 @default.
• W2048960987 cites W2151940807 @default.
• W2048960987 cites W2614129351 @default.
• W2048960987 doi "https://doi.org/10.1053/j.sodo.2008.02.008" @default.
• W2048960987 hasPublicationYear "2008" @default.
• W2048960987 type Work @default.
• W2048960987 sameAs 2048960987 @default.
• W2048960987 citedByCount "7" @default.
• W2048960987 countsByYear W20489609872012 @default.
• W2048960987 countsByYear W20489609872016 @default.
• W2048960987 countsByYear W20489609872017 @default.
• W2048960987 countsByYear W20489609872020 @default.
• W2048960987 crossrefType "journal-article" @default.
• W2048960987 hasAuthorship W2048960987A5035946946 @default.
• W2048960987 hasAuthorship W2048960987A5066911732 @default.
• W2048960987 hasConcept C104317684 @default.
• W2048960987 hasConcept C106934330 @default.
• W2048960987 hasConcept C120452360 @default.
• W2048960987 hasConcept C127716648 @default.
• W2048960987 hasConcept C142724271 @default.
• W2048960987 hasConcept C175783326 @default.
• W2048960987 hasConcept C199360897 @default.
• W2048960987 hasConcept C23085057 @default.
• W2048960987 hasConcept C2779134260 @default.
• W2048960987 hasConcept C2780902518 @default.
• W2048960987 hasConcept C2908647359 @default.
• W2048960987 hasConcept C2992519594 @default.
• W2048960987 hasConcept C41008148 @default.
• W2048960987 hasConcept C54355233 @default.
• W2048960987 hasConcept C71924100 @default.
• W2048960987 hasConcept C78458016 @default.
• W2048960987 hasConcept C81941488 @default.
• W2048960987 hasConcept C86803240 @default.
• W2048960987 hasConcept C9287583 @default.
• W2048960987 hasConcept C99454951 @default.
• W2048960987 hasConceptScore W2048960987C104317684 @default.
• W2048960987 hasConceptScore W2048960987C106934330 @default.
• W2048960987 hasConceptScore W2048960987C120452360 @default.
• W2048960987 hasConceptScore W2048960987C127716648 @default.
• W2048960987 hasConceptScore W2048960987C142724271 @default.
• W2048960987 hasConceptScore W2048960987C175783326 @default.
• W2048960987 hasConceptScore W2048960987C199360897 @default.
• W2048960987 hasConceptScore W2048960987C23085057 @default.
• W2048960987 hasConceptScore W2048960987C2779134260 @default.
• W2048960987 hasConceptScore W2048960987C2780902518 @default.
• W2048960987 hasConceptScore W2048960987C2908647359 @default.
• W2048960987 hasConceptScore W2048960987C2992519594 @default.
• W2048960987 hasConceptScore W2048960987C41008148 @default.
• W2048960987 hasConceptScore W2048960987C54355233 @default.
• W2048960987 hasConceptScore W2048960987C71924100 @default.
• W2048960987 hasConceptScore W2048960987C78458016 @default.
• W2048960987 hasConceptScore W2048960987C81941488 @default.
• W2048960987 hasConceptScore W2048960987C86803240 @default.
• W2048960987 hasConceptScore W2048960987C9287583 @default.
• W2048960987 hasConceptScore W2048960987C99454951 @default.
• W2048960987 hasIssue "2" @default.
• W2048960987 hasLocation W20489609871 @default.
• W2048960987 hasOpenAccess W2048960987 @default.
• W2048960987 hasPrimaryLocation W20489609871 @default.
• W2048960987 hasRelatedWork W1581494035 @default.
• W2048960987 hasRelatedWork W1991751528 @default.
• W2048960987 hasRelatedWork W2026718295 @default.
• W2048960987 hasRelatedWork W2033467220 @default.
• W2048960987 hasRelatedWork W2048960987 @default.
• W2048960987 hasRelatedWork W2060082218 @default.
• W2048960987 hasRelatedWork W2159975710 @default.
• W2048960987 hasRelatedWork W2974674048 @default.
• W2048960987 hasRelatedWork W4214764641 @default.
• W2048960987 hasRelatedWork W4254540204 @default.
• W2048960987 hasVolume "14" @default.
• W2048960987 isParatext "false" @default.
• W2048960987 isRetracted "false" @default.
• W2048960987 magId "2048960987" @default.
• W2048960987 workType "article" @default.