Matches in SemOpenAlex for { <https://semopenalex.org/work/W2048975057> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2048975057 endingPage "672" @default.
- W2048975057 startingPage "672" @default.
- W2048975057 abstract "Patients with decreased serum alpha1-antitrypsin were designated as severely deficient (7% to 15% of normal) or intermediately deficient (30% to 65% of normal) by quantitative radial immunodiffusion. All severely deficient patients were symptomatic and had severe emphysema. Among intermediately deficient patients emphysema was clinically evident only after age 50. Younger subjects had significant loss of lung elastic recoil and hyperinflation without expiratory flow obstruction. Older patients with an intermediate deficiency had abnormalities that were radiographically and physiologically identical to those of younger severely deficient patients. Postmortem examination of the lung of two patients with severe deficiency and one patient with intermediate deficiency showed extensive panlobular emphysema of the lower two thirds of the lungs, with relative sparing of the upper third. It is concluded that patients with intermediate alpha1-antitrypsin deficiency may develop emphysema identical to that found in severely deficient patients but at an older age." @default.
- W2048975057 created "2016-06-24" @default.
- W2048975057 creator A5003032874 @default.
- W2048975057 creator A5014389883 @default.
- W2048975057 creator A5018590434 @default.
- W2048975057 creator A5046129208 @default.
- W2048975057 date "1971-05-01" @default.
- W2048975057 modified "2023-10-16" @default.
- W2048975057 title "Pathophysiology of Hereditary Emphysema" @default.
- W2048975057 cites W1816359406 @default.
- W2048975057 cites W1862464476 @default.
- W2048975057 cites W1924569899 @default.
- W2048975057 cites W1974163309 @default.
- W2048975057 cites W1992992053 @default.
- W2048975057 cites W2001463961 @default.
- W2048975057 cites W2002983094 @default.
- W2048975057 cites W2005821682 @default.
- W2048975057 cites W2025313479 @default.
- W2048975057 cites W2025492091 @default.
- W2048975057 cites W2033932188 @default.
- W2048975057 cites W2094388155 @default.
- W2048975057 cites W2107052422 @default.
- W2048975057 cites W2180474633 @default.
- W2048975057 cites W2186589135 @default.
- W2048975057 cites W2235364015 @default.
- W2048975057 cites W2272789179 @default.
- W2048975057 cites W2312960054 @default.
- W2048975057 cites W2319554819 @default.
- W2048975057 cites W2406877803 @default.
- W2048975057 doi "https://doi.org/10.7326/0003-4819-74-5-672" @default.
- W2048975057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4104410" @default.
- W2048975057 hasPublicationYear "1971" @default.
- W2048975057 type Work @default.
- W2048975057 sameAs 2048975057 @default.
- W2048975057 citedByCount "45" @default.
- W2048975057 crossrefType "journal-article" @default.
- W2048975057 hasAuthorship W2048975057A5003032874 @default.
- W2048975057 hasAuthorship W2048975057A5014389883 @default.
- W2048975057 hasAuthorship W2048975057A5018590434 @default.
- W2048975057 hasAuthorship W2048975057A5046129208 @default.
- W2048975057 hasConcept C10162356 @default.
- W2048975057 hasConcept C126322002 @default.
- W2048975057 hasConcept C141071460 @default.
- W2048975057 hasConcept C142724271 @default.
- W2048975057 hasConcept C159654299 @default.
- W2048975057 hasConcept C203014093 @default.
- W2048975057 hasConcept C2777473361 @default.
- W2048975057 hasConcept C2777714996 @default.
- W2048975057 hasConcept C2780535462 @default.
- W2048975057 hasConcept C49651878 @default.
- W2048975057 hasConcept C71924100 @default.
- W2048975057 hasConcept C90924648 @default.
- W2048975057 hasConceptScore W2048975057C10162356 @default.
- W2048975057 hasConceptScore W2048975057C126322002 @default.
- W2048975057 hasConceptScore W2048975057C141071460 @default.
- W2048975057 hasConceptScore W2048975057C142724271 @default.
- W2048975057 hasConceptScore W2048975057C159654299 @default.
- W2048975057 hasConceptScore W2048975057C203014093 @default.
- W2048975057 hasConceptScore W2048975057C2777473361 @default.
- W2048975057 hasConceptScore W2048975057C2777714996 @default.
- W2048975057 hasConceptScore W2048975057C2780535462 @default.
- W2048975057 hasConceptScore W2048975057C49651878 @default.
- W2048975057 hasConceptScore W2048975057C71924100 @default.
- W2048975057 hasConceptScore W2048975057C90924648 @default.
- W2048975057 hasIssue "5" @default.
- W2048975057 hasLocation W20489750571 @default.
- W2048975057 hasLocation W20489750572 @default.
- W2048975057 hasOpenAccess W2048975057 @default.
- W2048975057 hasPrimaryLocation W20489750571 @default.
- W2048975057 hasRelatedWork W1586374228 @default.
- W2048975057 hasRelatedWork W2003938723 @default.
- W2048975057 hasRelatedWork W2045240138 @default.
- W2048975057 hasRelatedWork W2047967234 @default.
- W2048975057 hasRelatedWork W2118496982 @default.
- W2048975057 hasRelatedWork W2364998975 @default.
- W2048975057 hasRelatedWork W2369162477 @default.
- W2048975057 hasRelatedWork W2439875401 @default.
- W2048975057 hasRelatedWork W4238867864 @default.
- W2048975057 hasRelatedWork W2525756941 @default.
- W2048975057 hasVolume "74" @default.
- W2048975057 isParatext "false" @default.
- W2048975057 isRetracted "false" @default.
- W2048975057 magId "2048975057" @default.
- W2048975057 workType "article" @default.