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• W2048989833 abstract "Disruptive behavior disorders and obsessive-compulsive disorder have been associated with serotonergic dysfunction as well as particular body habitus findings in pediatric patients. Somatostatin, a peptide which stimulates serotonin release and inhibits growth hormone release, was measured in the cerebrospinal fluid (CSF) of 10 children with disruptive behavior disorders and in 10 age-, sex-, and race-matched pairs of obsessive-compulsive disorder patients. Decreased concentrations of somatostatin were found in disruptive behavior disorder patients relative to obsessive-compulsive children, even after controlling for differences in Tanner stage. In contrast to studies in adults, those patients in a depressed state did not have lower CSF somatostatin concentration." @default.
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• W2048989833 date "1990-09-01" @default.
• W2048989833 modified "2023-10-16" @default.
• W2048989833 title "CSF somatostatin in childhood psychiatric disorders: A preliminary investigation" @default.
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• W2048989833 doi "https://doi.org/10.1016/0165-1781(90)90044-6" @default.
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