Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049025824> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2049025824 endingPage "69" @default.
- W2049025824 startingPage "65" @default.
- W2049025824 abstract "1. Caffeine is widely used as an in vivo probe for CYP1A2; the distribution/activity of this enzyme is reported to be reflected by metabolic ratios. 2. Several metabolic ratios using different combinations of urinary metabolites have been used to measure CYP1A2, with varying conclusions on its distribution. 3. A mathematical comparison of five metabolic ratios claiming to reflect CYP1A2 activity was made using data from 237 healthy volunteers. 4. All five metabolic ratios were symmetrically distributed. The five ratios however, measured at least three different parameters, with no one ratio correlating exactly with any other. 5. Data in the literature claiming to measure CYP1A2 using caffeine may reflect other parameters. 6. The complex metabolism of caffeine together with different parameters controlling the renal clearance of each metabolite, makes the use of urinary metabolic ratios an inaccurate probe for assessing the distribution of CYP1A2 activity in populations." @default.
- W2049025824 created "2016-06-24" @default.
- W2049025824 creator A5024959919 @default.
- W2049025824 creator A5061529504 @default.
- W2049025824 creator A5084424690 @default.
- W2049025824 creator A5088130205 @default.
- W2049025824 creator A5089314960 @default.
- W2049025824 date "1995-01-01" @default.
- W2049025824 modified "2023-09-29" @default.
- W2049025824 title "Caffeine as a metabolic probe: a comparison of the metabolic ratios used to assess CYP1A2 activity." @default.
- W2049025824 cites W1977620197 @default.
- W2049025824 cites W1978541390 @default.
- W2049025824 cites W1984539710 @default.
- W2049025824 cites W1993780682 @default.
- W2049025824 cites W2007221068 @default.
- W2049025824 cites W2007469691 @default.
- W2049025824 cites W2035776430 @default.
- W2049025824 cites W2061061025 @default.
- W2049025824 cites W2068847386 @default.
- W2049025824 cites W2076313863 @default.
- W2049025824 cites W2084686194 @default.
- W2049025824 cites W2088342692 @default.
- W2049025824 cites W2093714545 @default.
- W2049025824 cites W2100199295 @default.
- W2049025824 cites W2105876917 @default.
- W2049025824 cites W2118402169 @default.
- W2049025824 cites W2158867214 @default.
- W2049025824 cites W2337652322 @default.
- W2049025824 cites W4233014035 @default.
- W2049025824 doi "https://doi.org/10.1111/j.1365-2125.1995.tb04411.x" @default.
- W2049025824 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1364983" @default.
- W2049025824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7756101" @default.
- W2049025824 hasPublicationYear "1995" @default.
- W2049025824 type Work @default.
- W2049025824 sameAs 2049025824 @default.
- W2049025824 citedByCount "36" @default.
- W2049025824 countsByYear W20490258242012 @default.
- W2049025824 countsByYear W20490258242019 @default.
- W2049025824 crossrefType "journal-article" @default.
- W2049025824 hasAuthorship W2049025824A5024959919 @default.
- W2049025824 hasAuthorship W2049025824A5061529504 @default.
- W2049025824 hasAuthorship W2049025824A5084424690 @default.
- W2049025824 hasAuthorship W2049025824A5088130205 @default.
- W2049025824 hasAuthorship W2049025824A5089314960 @default.
- W2049025824 hasBestOaLocation W20490258242 @default.
- W2049025824 hasConcept C126322002 @default.
- W2049025824 hasConcept C185592680 @default.
- W2049025824 hasConcept C2777477808 @default.
- W2049025824 hasConcept C2778500429 @default.
- W2049025824 hasConcept C2993927895 @default.
- W2049025824 hasConcept C42407357 @default.
- W2049025824 hasConcept C526171541 @default.
- W2049025824 hasConcept C55493867 @default.
- W2049025824 hasConcept C62231903 @default.
- W2049025824 hasConcept C71924100 @default.
- W2049025824 hasConcept C86745063 @default.
- W2049025824 hasConceptScore W2049025824C126322002 @default.
- W2049025824 hasConceptScore W2049025824C185592680 @default.
- W2049025824 hasConceptScore W2049025824C2777477808 @default.
- W2049025824 hasConceptScore W2049025824C2778500429 @default.
- W2049025824 hasConceptScore W2049025824C2993927895 @default.
- W2049025824 hasConceptScore W2049025824C42407357 @default.
- W2049025824 hasConceptScore W2049025824C526171541 @default.
- W2049025824 hasConceptScore W2049025824C55493867 @default.
- W2049025824 hasConceptScore W2049025824C62231903 @default.
- W2049025824 hasConceptScore W2049025824C71924100 @default.
- W2049025824 hasConceptScore W2049025824C86745063 @default.
- W2049025824 hasIssue "1" @default.
- W2049025824 hasLocation W20490258241 @default.
- W2049025824 hasLocation W20490258242 @default.
- W2049025824 hasLocation W20490258243 @default.
- W2049025824 hasLocation W20490258244 @default.
- W2049025824 hasOpenAccess W2049025824 @default.
- W2049025824 hasPrimaryLocation W20490258241 @default.
- W2049025824 hasRelatedWork W1499042971 @default.
- W2049025824 hasRelatedWork W1953472774 @default.
- W2049025824 hasRelatedWork W2005470532 @default.
- W2049025824 hasRelatedWork W2038091811 @default.
- W2049025824 hasRelatedWork W2041137397 @default.
- W2049025824 hasRelatedWork W2065514491 @default.
- W2049025824 hasRelatedWork W2087294835 @default.
- W2049025824 hasRelatedWork W2158009363 @default.
- W2049025824 hasRelatedWork W2313903586 @default.
- W2049025824 hasRelatedWork W2413097308 @default.
- W2049025824 hasVolume "39" @default.
- W2049025824 isParatext "false" @default.
- W2049025824 isRetracted "false" @default.
- W2049025824 magId "2049025824" @default.
- W2049025824 workType "article" @default.