Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049064995> ?p ?o ?g. }
- W2049064995 endingPage "129" @default.
- W2049064995 startingPage "119" @default.
- W2049064995 abstract "Binding sites for γ-aminobutyric acid, type B (GABAB), were measured in post-mortem brain samples (frontal cortex, temporal cortex, and hippocampus) from a group of suicide victims and a group of sex- and age-matched controls. Retrospective psychiatric diagnosis was performed, and only suicide victims with clear evidence of depression in the absence of symptoms of other psychiatric or neurological disorders were studied. There were no significant differences between depressed suicides and controls in the number or affinity of GABAB binding sites in the frontal or temporal cortex and no difference in GABAB binding (measured at two concentrations) in the hippocampus. Thirteen of the depressed suicides had not been prescribed antidepressant drugs recently, and none were found in their blood at post-mortem. The number of GABAB binding sites in the frontal and temporal cortex and GABAB binding in the hippocampus did not differ significantly between these drug-free suicides and matched controls. The Kd was higher, however, in the temporal cortex of the drug-free suicides than in the controls. A significant negative correlation was found between age and the number of GABAB binding sites in the temporal cortex (on the basis of pooled data from suicides and controls). These results indicate that GABAB binding sites are unaltered in the brains of depressed suicide victims." @default.
- W2049064995 created "2016-06-24" @default.
- W2049064995 creator A5004067750 @default.
- W2049064995 creator A5010649242 @default.
- W2049064995 creator A5018284364 @default.
- W2049064995 creator A5058798048 @default.
- W2049064995 creator A5082729263 @default.
- W2049064995 date "1988-11-01" @default.
- W2049064995 modified "2023-10-17" @default.
- W2049064995 title "Brain GABAB binding sites in depressed suicide victims" @default.
- W2049064995 cites W1490291762 @default.
- W2049064995 cites W1775749144 @default.
- W2049064995 cites W1967522045 @default.
- W2049064995 cites W1969502847 @default.
- W2049064995 cites W1985476786 @default.
- W2049064995 cites W1988104476 @default.
- W2049064995 cites W1988995470 @default.
- W2049064995 cites W2004019962 @default.
- W2049064995 cites W2004697417 @default.
- W2049064995 cites W2023830064 @default.
- W2049064995 cites W2042052682 @default.
- W2049064995 cites W2043462637 @default.
- W2049064995 cites W2050512750 @default.
- W2049064995 cites W2056606362 @default.
- W2049064995 cites W2059633455 @default.
- W2049064995 cites W2066900682 @default.
- W2049064995 cites W2070440890 @default.
- W2049064995 cites W2079974546 @default.
- W2049064995 cites W2083954196 @default.
- W2049064995 cites W2134996183 @default.
- W2049064995 cites W2144055043 @default.
- W2049064995 cites W2337622937 @default.
- W2049064995 cites W2415540009 @default.
- W2049064995 cites W2417059513 @default.
- W2049064995 cites W4236316486 @default.
- W2049064995 doi "https://doi.org/10.1016/0165-1781(88)90066-2" @default.
- W2049064995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2853398" @default.
- W2049064995 hasPublicationYear "1988" @default.
- W2049064995 type Work @default.
- W2049064995 sameAs 2049064995 @default.
- W2049064995 citedByCount "54" @default.
- W2049064995 countsByYear W20490649952012 @default.
- W2049064995 countsByYear W20490649952014 @default.
- W2049064995 countsByYear W20490649952015 @default.
- W2049064995 countsByYear W20490649952016 @default.
- W2049064995 countsByYear W20490649952017 @default.
- W2049064995 countsByYear W20490649952018 @default.
- W2049064995 countsByYear W20490649952019 @default.
- W2049064995 countsByYear W20490649952020 @default.
- W2049064995 countsByYear W20490649952022 @default.
- W2049064995 crossrefType "journal-article" @default.
- W2049064995 hasAuthorship W2049064995A5004067750 @default.
- W2049064995 hasAuthorship W2049064995A5010649242 @default.
- W2049064995 hasAuthorship W2049064995A5018284364 @default.
- W2049064995 hasAuthorship W2049064995A5058798048 @default.
- W2049064995 hasAuthorship W2049064995A5082729263 @default.
- W2049064995 hasConcept C101027131 @default.
- W2049064995 hasConcept C118552586 @default.
- W2049064995 hasConcept C126322002 @default.
- W2049064995 hasConcept C134018914 @default.
- W2049064995 hasConcept C139719470 @default.
- W2049064995 hasConcept C15744967 @default.
- W2049064995 hasConcept C162324750 @default.
- W2049064995 hasConcept C168258287 @default.
- W2049064995 hasConcept C169760540 @default.
- W2049064995 hasConcept C170493617 @default.
- W2049064995 hasConcept C2776867660 @default.
- W2049064995 hasConcept C2777348757 @default.
- W2049064995 hasConcept C2779177272 @default.
- W2049064995 hasConcept C2781161787 @default.
- W2049064995 hasConcept C2993858690 @default.
- W2049064995 hasConcept C71924100 @default.
- W2049064995 hasConceptScore W2049064995C101027131 @default.
- W2049064995 hasConceptScore W2049064995C118552586 @default.
- W2049064995 hasConceptScore W2049064995C126322002 @default.
- W2049064995 hasConceptScore W2049064995C134018914 @default.
- W2049064995 hasConceptScore W2049064995C139719470 @default.
- W2049064995 hasConceptScore W2049064995C15744967 @default.
- W2049064995 hasConceptScore W2049064995C162324750 @default.
- W2049064995 hasConceptScore W2049064995C168258287 @default.
- W2049064995 hasConceptScore W2049064995C169760540 @default.
- W2049064995 hasConceptScore W2049064995C170493617 @default.
- W2049064995 hasConceptScore W2049064995C2776867660 @default.
- W2049064995 hasConceptScore W2049064995C2777348757 @default.
- W2049064995 hasConceptScore W2049064995C2779177272 @default.
- W2049064995 hasConceptScore W2049064995C2781161787 @default.
- W2049064995 hasConceptScore W2049064995C2993858690 @default.
- W2049064995 hasConceptScore W2049064995C71924100 @default.
- W2049064995 hasIssue "2" @default.
- W2049064995 hasLocation W20490649951 @default.
- W2049064995 hasLocation W20490649952 @default.
- W2049064995 hasOpenAccess W2049064995 @default.
- W2049064995 hasPrimaryLocation W20490649951 @default.
- W2049064995 hasRelatedWork W2056798802 @default.
- W2049064995 hasRelatedWork W2130000240 @default.
- W2049064995 hasRelatedWork W2351364982 @default.
- W2049064995 hasRelatedWork W2376792881 @default.
- W2049064995 hasRelatedWork W2386159701 @default.