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- W2049065588 abstract "Marine organisms have been reported to be a rich source of biologically active compounds, but when compared with plants, their use is much more restrict in popular medicine. Among marine animals, sponges and ascidians are two of the most prominent sources of new compounds with cytotoxic potential. In this study, we tested 40 extracts of marine sponges and ascidians from southeastern Brazilian coast aiming to evaluate their anti-proliferative effects on cultured cells. The extracts of Amorphinopsis sp., Arenosclera brasilensis, Cystodytes dellechiajei, Cliona aff. celata, Didemnum sp., Hadromerida and Scopalina ruetzleri showed an IC50≤30 μg/mL and produce strong effects on microtubules organization and on the cell cycle progression." @default.
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- W2049065588 date "2004-12-01" @default.
- W2049065588 modified "2023-09-29" @default.
- W2049065588 title "Effects of marine organisms extracts on microtubule integrity and cell cycle progression in cultured cells" @default.
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- W2049065588 doi "https://doi.org/10.1016/j.jembe.2004.08.008" @default.
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