Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049121569> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2049121569 endingPage "56" @default.
- W2049121569 startingPage "41" @default.
- W2049121569 abstract "The physicochemical properties of pharmaceuticals such as acid dissociation constant (pK), octanol-water partition coefficient (logP), protein binding constant, inclusion complex constant with cyclodextrin (CD), and selfassociation are very important in drug design, candidate selection, and drug delivery. Capillary electrophoresis (CE) is a simple, versatile, automated, and powerful separation technique and widely applied in physicochemical profiling for pharmaceuticals. It has advantages over traditional potentiometric, spectrophotometric, chromatographic, and other methods, as CE requires very small amounts of sample and can measure compounds with impurities and low aqueous solubility. Principles and applications of CE in profiling various physicochemical properties will be reviewed. Keywords: capillary electrophoresis, acid dissociation constant, octanol-water partition coefficient, drug-protein binding, inclusion complex constant, self-association" @default.
- W2049121569 created "2016-06-24" @default.
- W2049121569 creator A5021156605 @default.
- W2049121569 date "2005-01-01" @default.
- W2049121569 modified "2023-10-07" @default.
- W2049121569 title "Physicochemical Profiling by Capillary Electrophoresis" @default.
- W2049121569 cites W1501372585 @default.
- W2049121569 cites W1537867938 @default.
- W2049121569 cites W1566111314 @default.
- W2049121569 cites W600117423 @default.
- W2049121569 cites W651444216 @default.
- W2049121569 doi "https://doi.org/10.2174/1573412052953319" @default.
- W2049121569 hasPublicationYear "2005" @default.
- W2049121569 type Work @default.
- W2049121569 sameAs 2049121569 @default.
- W2049121569 citedByCount "45" @default.
- W2049121569 countsByYear W20491215692012 @default.
- W2049121569 countsByYear W20491215692013 @default.
- W2049121569 countsByYear W20491215692014 @default.
- W2049121569 countsByYear W20491215692015 @default.
- W2049121569 countsByYear W20491215692016 @default.
- W2049121569 countsByYear W20491215692017 @default.
- W2049121569 crossrefType "journal-article" @default.
- W2049121569 hasAuthorship W2049121569A5021156605 @default.
- W2049121569 hasConcept C113196181 @default.
- W2049121569 hasConcept C124614425 @default.
- W2049121569 hasConcept C145148216 @default.
- W2049121569 hasConcept C155574463 @default.
- W2049121569 hasConcept C170493617 @default.
- W2049121569 hasConcept C178790620 @default.
- W2049121569 hasConcept C184651966 @default.
- W2049121569 hasConcept C185592680 @default.
- W2049121569 hasConcept C192552737 @default.
- W2049121569 hasConcept C22163223 @default.
- W2049121569 hasConcept C2779433975 @default.
- W2049121569 hasConcept C2900643 @default.
- W2049121569 hasConcept C40250595 @default.
- W2049121569 hasConcept C43617362 @default.
- W2049121569 hasConcept C55493867 @default.
- W2049121569 hasConcept C74998103 @default.
- W2049121569 hasConceptScore W2049121569C113196181 @default.
- W2049121569 hasConceptScore W2049121569C124614425 @default.
- W2049121569 hasConceptScore W2049121569C145148216 @default.
- W2049121569 hasConceptScore W2049121569C155574463 @default.
- W2049121569 hasConceptScore W2049121569C170493617 @default.
- W2049121569 hasConceptScore W2049121569C178790620 @default.
- W2049121569 hasConceptScore W2049121569C184651966 @default.
- W2049121569 hasConceptScore W2049121569C185592680 @default.
- W2049121569 hasConceptScore W2049121569C192552737 @default.
- W2049121569 hasConceptScore W2049121569C22163223 @default.
- W2049121569 hasConceptScore W2049121569C2779433975 @default.
- W2049121569 hasConceptScore W2049121569C2900643 @default.
- W2049121569 hasConceptScore W2049121569C40250595 @default.
- W2049121569 hasConceptScore W2049121569C43617362 @default.
- W2049121569 hasConceptScore W2049121569C55493867 @default.
- W2049121569 hasConceptScore W2049121569C74998103 @default.
- W2049121569 hasIssue "1" @default.
- W2049121569 hasLocation W20491215691 @default.
- W2049121569 hasOpenAccess W2049121569 @default.
- W2049121569 hasPrimaryLocation W20491215691 @default.
- W2049121569 hasRelatedWork W167626745 @default.
- W2049121569 hasRelatedWork W1997851828 @default.
- W2049121569 hasRelatedWork W2010565079 @default.
- W2049121569 hasRelatedWork W2033917390 @default.
- W2049121569 hasRelatedWork W2041078592 @default.
- W2049121569 hasRelatedWork W2086541512 @default.
- W2049121569 hasRelatedWork W2151842546 @default.
- W2049121569 hasRelatedWork W2163863726 @default.
- W2049121569 hasRelatedWork W3014754812 @default.
- W2049121569 hasRelatedWork W4286523199 @default.
- W2049121569 hasVolume "1" @default.
- W2049121569 isParatext "false" @default.
- W2049121569 isRetracted "false" @default.
- W2049121569 magId "2049121569" @default.
- W2049121569 workType "article" @default.