FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049133091> ?p ?o ?g. }

• W2049133091 endingPage "9255" @default.
• W2049133091 startingPage "9250" @default.
• W2049133091 abstract "Human protein Z (PZ) is a 62,000-Mr, vitamin K-dependent plasma protein whose structure is similar to coagulation factors VII, IX, X, protein C, and protein S, but whose function is not known. The procoagulant activity of factor Xa in a one-stage plasma coagulation assay is reduced when factor Xa is first incubated with PZ. This apparent inhibitory effect is time dependent, requires the presence of calcium ions and procoagulant phospholipids (rabbit brain cephalin), and appears predominantly related to the incubation period of PZ with cephalin. In serum the initial rate of inhibition of factor Xa with calcium ions and cephalin also is enhanced in the presence PZ. A PZ-dependent protease inhibitor (ZPI) has been isolated from plasma. ZPI is a 72,000-Mr single-chain protein with an N-terminal amino acid sequence of LAPSPQSPEXXA (X = indeterminate) and an estimated concentration in citrate-treated plasma of 1.0-1.6 microg/ml. In systems using purified components, the factor Xa inhibition produced by ZPI is rapid (>95% within 1 min by coagulation assay) and requires the presence of PZ, calcium ions, and cephalin. The inhibitory process appears to involve the formation of a factor Xa-PZ-ZPI complex at the phospholipid surface." @default.
• W2049133091 created "2016-06-24" @default.
• W2049133091 creator A5011882390 @default.
• W2049133091 creator A5040090678 @default.
• W2049133091 creator A5069214916 @default.
• W2049133091 date "1998-08-04" @default.
• W2049133091 modified "2023-10-13" @default.
• W2049133091 title "Isolation of a protein Z-dependent plasma protease inhibitor" @default.
• W2049133091 cites W1498794674 @default.
• W2049133091 cites W1549602366 @default.
• W2049133091 cites W1559610250 @default.
• W2049133091 cites W1635858559 @default.
• W2049133091 cites W1782728159 @default.
• W2049133091 cites W1975787873 @default.
• W2049133091 cites W1996675508 @default.
• W2049133091 cites W2018289835 @default.
• W2049133091 cites W2035878470 @default.
• W2049133091 cites W2037679157 @default.
• W2049133091 cites W2043108703 @default.
• W2049133091 cites W2083303730 @default.
• W2049133091 cites W2097993282 @default.
• W2049133091 cites W2100837269 @default.
• W2049133091 cites W2128788780 @default.
• W2049133091 cites W2170055655 @default.
• W2049133091 cites W64286279 @default.
• W2049133091 doi "https://doi.org/10.1073/pnas.95.16.9250" @default.
• W2049133091 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/21324" @default.
• W2049133091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9689066" @default.
• W2049133091 hasPublicationYear "1998" @default.
• W2049133091 type Work @default.
• W2049133091 sameAs 2049133091 @default.
• W2049133091 citedByCount "126" @default.
• W2049133091 countsByYear W20491330912012 @default.
• W2049133091 countsByYear W20491330912013 @default.
• W2049133091 countsByYear W20491330912014 @default.
• W2049133091 countsByYear W20491330912015 @default.
• W2049133091 countsByYear W20491330912016 @default.
• W2049133091 countsByYear W20491330912017 @default.
• W2049133091 countsByYear W20491330912018 @default.
• W2049133091 countsByYear W20491330912019 @default.
• W2049133091 countsByYear W20491330912020 @default.
• W2049133091 countsByYear W20491330912021 @default.
• W2049133091 countsByYear W20491330912022 @default.
• W2049133091 crossrefType "journal-article" @default.
• W2049133091 hasAuthorship W2049133091A5011882390 @default.
• W2049133091 hasAuthorship W2049133091A5040090678 @default.
• W2049133091 hasAuthorship W2049133091A5069214916 @default.
• W2049133091 hasBestOaLocation W20491330911 @default.
• W2049133091 hasConcept C126322002 @default.
• W2049133091 hasConcept C178790620 @default.
• W2049133091 hasConcept C181199279 @default.
• W2049133091 hasConcept C185592680 @default.
• W2049133091 hasConcept C203014093 @default.
• W2049133091 hasConcept C25642318 @default.
• W2049133091 hasConcept C2776714187 @default.
• W2049133091 hasConcept C2777292125 @default.
• W2049133091 hasConcept C2777444498 @default.
• W2049133091 hasConcept C2778382381 @default.
• W2049133091 hasConcept C2778918659 @default.
• W2049133091 hasConcept C41625074 @default.
• W2049133091 hasConcept C43617362 @default.
• W2049133091 hasConcept C515207424 @default.
• W2049133091 hasConcept C519063684 @default.
• W2049133091 hasConcept C55493867 @default.
• W2049133091 hasConcept C71924100 @default.
• W2049133091 hasConcept C86803240 @default.
• W2049133091 hasConcept C89560881 @default.
• W2049133091 hasConceptScore W2049133091C126322002 @default.
• W2049133091 hasConceptScore W2049133091C178790620 @default.
• W2049133091 hasConceptScore W2049133091C181199279 @default.
• W2049133091 hasConceptScore W2049133091C185592680 @default.
• W2049133091 hasConceptScore W2049133091C203014093 @default.
• W2049133091 hasConceptScore W2049133091C25642318 @default.
• W2049133091 hasConceptScore W2049133091C2776714187 @default.
• W2049133091 hasConceptScore W2049133091C2777292125 @default.
• W2049133091 hasConceptScore W2049133091C2777444498 @default.
• W2049133091 hasConceptScore W2049133091C2778382381 @default.
• W2049133091 hasConceptScore W2049133091C2778918659 @default.
• W2049133091 hasConceptScore W2049133091C41625074 @default.
• W2049133091 hasConceptScore W2049133091C43617362 @default.
• W2049133091 hasConceptScore W2049133091C515207424 @default.
• W2049133091 hasConceptScore W2049133091C519063684 @default.
• W2049133091 hasConceptScore W2049133091C55493867 @default.
• W2049133091 hasConceptScore W2049133091C71924100 @default.
• W2049133091 hasConceptScore W2049133091C86803240 @default.
• W2049133091 hasConceptScore W2049133091C89560881 @default.
• W2049133091 hasIssue "16" @default.
• W2049133091 hasLocation W20491330911 @default.
• W2049133091 hasLocation W20491330912 @default.
• W2049133091 hasLocation W20491330913 @default.
• W2049133091 hasLocation W20491330914 @default.
• W2049133091 hasOpenAccess W2049133091 @default.
• W2049133091 hasPrimaryLocation W20491330911 @default.
• W2049133091 hasRelatedWork W1717503047 @default.
• W2049133091 hasRelatedWork W1780974004 @default.
• W2049133091 hasRelatedWork W1963985231 @default.
• W2049133091 hasRelatedWork W2051645514 @default.
• W2049133091 hasRelatedWork W2079454393 @default.

• next