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- W2049191567 abstract "Malignant fibrous histiocytoma (MFH), arising at the site of a sacral chordoma 8 years after massive radiotherapy, is described. Initially, the patient received 7000 rad to the sacral area and, on recurrence, 5 years later, an additional 4000 rad. Two years later, a sacral mass was noted again. Biopsy then revealed MFH; chest x-ray showed multiple lung metastases. A combination chemotherapy, consisting of cyclophosphamide, vincristine, adriamycin (doxorubicin), and DTIC, resulted in a 6 month partial response. Subsequently, the patient died because of progressive metastatic disease. At autopsy, 8 years after diagnosis, both the sacral lesion and the lung metastases proved to be MFH, and no residual chordoma was found." @default.
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- W2049191567 date "1984-06-15" @default.
- W2049191567 modified "2023-09-24" @default.
- W2049191567 title "Malignant fibrous histiocytoma developing in irradiated sacral chordoma" @default.
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- W2049191567 doi "https://doi.org/10.1002/1097-0142(19840615)53:12<2661::aid-cncr2820531215>3.0.co;2-6" @default.
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