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- W2049195633 abstract "To the Editor: On the basis of the observations of Seiler and Duckert1 that the addition of sulfinpyrazone to plasma displaced phenprocoumon from protein-binding sites, Koch-Weser and Sellers2 predicted that the administration of sulfinpyrazone to patients chronically treated with coumarins would potentiate anticoagulation. Our recent observations of the prothrombin time of a 53-year-old man with recurrent thromboembolism suggest that their prediction was correct. The prothrombin time had been maintained between 16 and 24 seconds for two months while he received 5 mg of warfarin each day with the exception of two days when it was omitted. One week after he . . ." @default.
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- W2049195633 date "1978-10-26" @default.
- W2049195633 modified "2023-10-18" @default.
- W2049195633 title "Possible Interaction of Sulfinpyrazone with Coumarins" @default.
- W2049195633 cites W1975137698 @default.
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- W2049195633 doi "https://doi.org/10.1056/nejm197810262991715" @default.
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