Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049209994> ?p ?o ?g. }
- W2049209994 endingPage "687" @default.
- W2049209994 startingPage "681" @default.
- W2049209994 abstract "Systematic use of next-generation sequencing technologies has transformed the field of cancer genomics, leading to the identification of genetic alterations in an unanticipated number of genes and regulatory elements. Here, we review recent advances in brain tumour genomics and highlight how these findings improve classification and diagnosis of brain tumours.The studies discussed in this review have shed light on different areas of neuro-oncology. In-depth analysis of paediatric low-grade gliomas as well as paediatric glioblastomas has clarified our molecular understanding of these diseases, clearly distinguishing them from their adult counterparts. Unexpected novel mutations have been discovered in adult low-grade astrocytomas and in glioblastomas. Novel studies also highlighted candidate tumour suppressor genes located on the chromosome arms frequently deleted in oligodendrogliomas. Finally, we review recent discoveries in the molecular landscapes of medulloblastomas and meningiomas.These recent studies begin to provide an in-depth view of the molecular routes leading to brain tumour development. The findings will be critical for refining classification systems and improving clinical management." @default.
- W2049209994 created "2016-06-24" @default.
- W2049209994 creator A5013741617 @default.
- W2049209994 creator A5021122229 @default.
- W2049209994 date "2013-12-01" @default.
- W2049209994 modified "2023-09-27" @default.
- W2049209994 title "Next-generation molecular genetics of brain tumours" @default.
- W2049209994 cites W1492082915 @default.
- W2049209994 cites W1921809757 @default.
- W2049209994 cites W1930097530 @default.
- W2049209994 cites W1971176522 @default.
- W2049209994 cites W1974625077 @default.
- W2049209994 cites W1979068808 @default.
- W2049209994 cites W1979855662 @default.
- W2049209994 cites W1984053802 @default.
- W2049209994 cites W1989891384 @default.
- W2049209994 cites W1995105508 @default.
- W2049209994 cites W1999831372 @default.
- W2049209994 cites W2000381516 @default.
- W2049209994 cites W2004456850 @default.
- W2049209994 cites W2005036868 @default.
- W2049209994 cites W2015328333 @default.
- W2049209994 cites W2021630037 @default.
- W2049209994 cites W2022064821 @default.
- W2049209994 cites W2033130827 @default.
- W2049209994 cites W2035346960 @default.
- W2049209994 cites W2038120157 @default.
- W2049209994 cites W2039379153 @default.
- W2049209994 cites W2040827479 @default.
- W2049209994 cites W2045711626 @default.
- W2049209994 cites W2061015740 @default.
- W2049209994 cites W2062062519 @default.
- W2049209994 cites W2090757807 @default.
- W2049209994 cites W2091643194 @default.
- W2049209994 cites W2118124054 @default.
- W2049209994 cites W2127931233 @default.
- W2049209994 cites W2131117209 @default.
- W2049209994 cites W2135035484 @default.
- W2049209994 cites W2135656436 @default.
- W2049209994 cites W2142630775 @default.
- W2049209994 cites W2145489645 @default.
- W2049209994 cites W2154170543 @default.
- W2049209994 cites W2158233796 @default.
- W2049209994 cites W2166798417 @default.
- W2049209994 cites W2167532631 @default.
- W2049209994 cites W2171425841 @default.
- W2049209994 doi "https://doi.org/10.1097/wco.0000000000000027" @default.
- W2049209994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24184972" @default.
- W2049209994 hasPublicationYear "2013" @default.
- W2049209994 type Work @default.
- W2049209994 sameAs 2049209994 @default.
- W2049209994 citedByCount "15" @default.
- W2049209994 countsByYear W20492099942015 @default.
- W2049209994 countsByYear W20492099942017 @default.
- W2049209994 countsByYear W20492099942018 @default.
- W2049209994 countsByYear W20492099942019 @default.
- W2049209994 countsByYear W20492099942020 @default.
- W2049209994 countsByYear W20492099942021 @default.
- W2049209994 countsByYear W20492099942022 @default.
- W2049209994 crossrefType "journal-article" @default.
- W2049209994 hasAuthorship W2049209994A5013741617 @default.
- W2049209994 hasAuthorship W2049209994A5021122229 @default.
- W2049209994 hasConcept C104317684 @default.
- W2049209994 hasConcept C116834253 @default.
- W2049209994 hasConcept C141231307 @default.
- W2049209994 hasConcept C189206191 @default.
- W2049209994 hasConcept C54355233 @default.
- W2049209994 hasConcept C59822182 @default.
- W2049209994 hasConcept C60644358 @default.
- W2049209994 hasConcept C70721500 @default.
- W2049209994 hasConcept C71924100 @default.
- W2049209994 hasConcept C86803240 @default.
- W2049209994 hasConceptScore W2049209994C104317684 @default.
- W2049209994 hasConceptScore W2049209994C116834253 @default.
- W2049209994 hasConceptScore W2049209994C141231307 @default.
- W2049209994 hasConceptScore W2049209994C189206191 @default.
- W2049209994 hasConceptScore W2049209994C54355233 @default.
- W2049209994 hasConceptScore W2049209994C59822182 @default.
- W2049209994 hasConceptScore W2049209994C60644358 @default.
- W2049209994 hasConceptScore W2049209994C70721500 @default.
- W2049209994 hasConceptScore W2049209994C71924100 @default.
- W2049209994 hasConceptScore W2049209994C86803240 @default.
- W2049209994 hasIssue "6" @default.
- W2049209994 hasLocation W20492099941 @default.
- W2049209994 hasLocation W20492099942 @default.
- W2049209994 hasOpenAccess W2049209994 @default.
- W2049209994 hasPrimaryLocation W20492099941 @default.
- W2049209994 hasRelatedWork W1018654837 @default.
- W2049209994 hasRelatedWork W1885916946 @default.
- W2049209994 hasRelatedWork W2048130697 @default.
- W2049209994 hasRelatedWork W2168223719 @default.
- W2049209994 hasRelatedWork W2338361349 @default.
- W2049209994 hasRelatedWork W2518703062 @default.
- W2049209994 hasRelatedWork W2998655779 @default.
- W2049209994 hasRelatedWork W3036466965 @default.
- W2049209994 hasRelatedWork W4249203378 @default.
- W2049209994 hasRelatedWork W86516035 @default.
- W2049209994 hasVolume "26" @default.