Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049253400> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2049253400 endingPage "219" @default.
- W2049253400 startingPage "215" @default.
- W2049253400 abstract "Objective: To determine the effects of tibolone, a synthetic steroid used to alleviate climacteric symptoms and prevent osteoporosis, on lipoprotein metabolism, with particular reference to lipoprotein(a) levels and HDL subfraction profiles.Design: Thirty nine postmenopausal women were treated with tibolone (Livial) 2.5 mg/day for 6 months and fasting serum lipoprotein levels were estimated at 0, 2, 4 and 6 months. Results: Lipoprotein(a) levels were reduced significantly over the 6 months from a median level of 245 (range <60–780) mg/I to 152 (range <60–530) mg/l, a reduction of 39% in the median level. A decrease was observed in approximately two thirds of the women. Reductions were noted in all 6 subjects whose pretreatment levels were high, although concentrations remained at a level associated with increased risk in all but one. There were significant decreases in triglycerides and VLDL cholesterol and no significant change in LDL cholesterol. There was a significant reduction of 18% in HDL cholesterol and a 26% reduction in the HDL2:HDL3 ratio. Conclusion: The reduction in lipoprotein(a) levels may have a beneficial effect on cardiovascular risk, which could go some way towards balancing the potentially adverse effect on the cardiovascular system caused by the reduction in HDL cholesterol." @default.
- W2049253400 created "2016-06-24" @default.
- W2049253400 creator A5001388272 @default.
- W2049253400 creator A5051108040 @default.
- W2049253400 creator A5052686429 @default.
- W2049253400 creator A5075231286 @default.
- W2049253400 creator A5089759175 @default.
- W2049253400 creator A5065398623 @default.
- W2049253400 date "1994-12-01" @default.
- W2049253400 modified "2023-10-16" @default.
- W2049253400 title "Effects of tibolone on lipoprotein(a) and HDL subfractions" @default.
- W2049253400 cites W1967836568 @default.
- W2049253400 cites W1972918687 @default.
- W2049253400 cites W1973784412 @default.
- W2049253400 cites W1989614437 @default.
- W2049253400 cites W2000101966 @default.
- W2049253400 cites W2006124505 @default.
- W2049253400 cites W2026453151 @default.
- W2049253400 cites W2031731441 @default.
- W2049253400 cites W2048182846 @default.
- W2049253400 cites W2052998518 @default.
- W2049253400 cites W2072537818 @default.
- W2049253400 cites W2073262028 @default.
- W2049253400 cites W2081496304 @default.
- W2049253400 cites W2084568943 @default.
- W2049253400 cites W2086684542 @default.
- W2049253400 cites W2089712285 @default.
- W2049253400 cites W2089719674 @default.
- W2049253400 cites W2106002344 @default.
- W2049253400 cites W2127857303 @default.
- W2049253400 cites W2133778284 @default.
- W2049253400 cites W2147811844 @default.
- W2049253400 cites W2337032743 @default.
- W2049253400 cites W2395035696 @default.
- W2049253400 cites W4234847005 @default.
- W2049253400 doi "https://doi.org/10.1016/0378-5122(94)90019-1" @default.
- W2049253400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7715475" @default.
- W2049253400 hasPublicationYear "1994" @default.
- W2049253400 type Work @default.
- W2049253400 sameAs 2049253400 @default.
- W2049253400 citedByCount "43" @default.
- W2049253400 crossrefType "journal-article" @default.
- W2049253400 hasAuthorship W2049253400A5001388272 @default.
- W2049253400 hasAuthorship W2049253400A5051108040 @default.
- W2049253400 hasAuthorship W2049253400A5052686429 @default.
- W2049253400 hasAuthorship W2049253400A5065398623 @default.
- W2049253400 hasAuthorship W2049253400A5075231286 @default.
- W2049253400 hasAuthorship W2049253400A5089759175 @default.
- W2049253400 hasConcept C126322002 @default.
- W2049253400 hasConcept C134018914 @default.
- W2049253400 hasConcept C198454886 @default.
- W2049253400 hasConcept C2776104379 @default.
- W2049253400 hasConcept C2776541429 @default.
- W2049253400 hasConcept C2777457466 @default.
- W2049253400 hasConcept C2778163477 @default.
- W2049253400 hasConcept C2778562196 @default.
- W2049253400 hasConcept C2780072125 @default.
- W2049253400 hasConcept C71924100 @default.
- W2049253400 hasConcept C8243546 @default.
- W2049253400 hasConceptScore W2049253400C126322002 @default.
- W2049253400 hasConceptScore W2049253400C134018914 @default.
- W2049253400 hasConceptScore W2049253400C198454886 @default.
- W2049253400 hasConceptScore W2049253400C2776104379 @default.
- W2049253400 hasConceptScore W2049253400C2776541429 @default.
- W2049253400 hasConceptScore W2049253400C2777457466 @default.
- W2049253400 hasConceptScore W2049253400C2778163477 @default.
- W2049253400 hasConceptScore W2049253400C2778562196 @default.
- W2049253400 hasConceptScore W2049253400C2780072125 @default.
- W2049253400 hasConceptScore W2049253400C71924100 @default.
- W2049253400 hasConceptScore W2049253400C8243546 @default.
- W2049253400 hasIssue "2-3" @default.
- W2049253400 hasLocation W20492534001 @default.
- W2049253400 hasLocation W20492534002 @default.
- W2049253400 hasOpenAccess W2049253400 @default.
- W2049253400 hasPrimaryLocation W20492534001 @default.
- W2049253400 hasRelatedWork W2084706508 @default.
- W2049253400 hasRelatedWork W2094541429 @default.
- W2049253400 hasRelatedWork W2104077048 @default.
- W2049253400 hasRelatedWork W2127668191 @default.
- W2049253400 hasRelatedWork W2137411754 @default.
- W2049253400 hasRelatedWork W2379411053 @default.
- W2049253400 hasRelatedWork W4237889996 @default.
- W2049253400 hasRelatedWork W4238105569 @default.
- W2049253400 hasRelatedWork W648640691 @default.
- W2049253400 hasRelatedWork W2336395065 @default.
- W2049253400 hasVolume "20" @default.
- W2049253400 isParatext "false" @default.
- W2049253400 isRetracted "false" @default.
- W2049253400 magId "2049253400" @default.
- W2049253400 workType "article" @default.