Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049279006> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2049279006 endingPage "259" @default.
- W2049279006 startingPage "254" @default.
- W2049279006 abstract "To measure the levels of oxidation and peroxidation products of membrane constituents chiefly lipids produced by oxygen and lipid free radicals as thiobarbituric acid reacting substances (TBARS), reduced glutathione (GSH) and the antioxidant enzymes, superoxide dismutase (SOD) and glutathione peroxidase (GP) in vitreous samples from patients with Eales' disease and estimate GSH, SOD, GP in the erythrocytes of patients with Eales' disease with active perivasculitis and healed perivasculitis.Vitreous samples on vitrectomy from 11 patients with Eales' disease and 11 patients with diabetic vitreous hemorrhage were used for comparison. For study on erythrocytes, 30 patients of Eales' disease at the active vasculitis stage (group-I), 33 of healed vasculitis stage (group-II) and 25 controls (group-III) were used. The male female ratio was kept the same among the patients and the controls. Oxidation and peroxidation products of membrane constituents chiefly lipids were estimated as TBARS, SOD by its activity to inhibit auto-oxidation of epinephrine, GP by estimating the reduction in the level of GSH and GSH by its colour reaction with 5,5'-dithio bis (2-nitro) benzoic acid (DTNB).TBARS were increased 6 fold in the vitreous of Eales' patients compared to the samples from those with diabetic vitreous hemorrhage while there was a reduction of 95.9% of SOD and 84.2% of GSH. Activity of SOD, GP and the levels of GSH in the erythrocytes were reduced (%) by 81.6, 65 and 56.5 respectively in group I and 22,46.4 and 29.2% respectively in group II. The values are statistically significant.Increased levels of TBARS and decreased levels of SOD and GSH in the vitreous could explain inflammation, retinal damage and neovascularization in patients with Eales' disease. Decrease of SOD, GP and GSH is found in erythrocytes both in the active perivasculitis stage and the healed perivasculitis stage. Treatment of Eales' disease with antioxidants vitamin E, C as also vitamin A may have a beneficial effect." @default.
- W2049279006 created "2016-06-24" @default.
- W2049279006 creator A5006420679 @default.
- W2049279006 creator A5010148762 @default.
- W2049279006 creator A5042232456 @default.
- W2049279006 date "1999-01-01" @default.
- W2049279006 modified "2023-09-25" @default.
- W2049279006 title "Eales' disease: increased oxidation and peroxidation products of membrane constituents chiefly lipids and decreased antioxidant enzymes and reduced glutathione in vitreous" @default.
- W2049279006 cites W1639879535 @default.
- W2049279006 cites W1750690213 @default.
- W2049279006 cites W1775749144 @default.
- W2049279006 cites W1963885414 @default.
- W2049279006 cites W1977898989 @default.
- W2049279006 cites W1996452351 @default.
- W2049279006 cites W2013238661 @default.
- W2049279006 cites W2014840970 @default.
- W2049279006 cites W2020194363 @default.
- W2049279006 cites W2060194897 @default.
- W2049279006 cites W2092552353 @default.
- W2049279006 doi "https://doi.org/10.1076/ceyr.19.3.254.5312" @default.
- W2049279006 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10487964" @default.
- W2049279006 hasPublicationYear "1999" @default.
- W2049279006 type Work @default.
- W2049279006 sameAs 2049279006 @default.
- W2049279006 citedByCount "27" @default.
- W2049279006 countsByYear W20492790062012 @default.
- W2049279006 countsByYear W20492790062013 @default.
- W2049279006 countsByYear W20492790062016 @default.
- W2049279006 countsByYear W20492790062017 @default.
- W2049279006 countsByYear W20492790062019 @default.
- W2049279006 countsByYear W20492790062020 @default.
- W2049279006 countsByYear W20492790062021 @default.
- W2049279006 countsByYear W20492790062022 @default.
- W2049279006 crossrefType "journal-article" @default.
- W2049279006 hasAuthorship W2049279006A5006420679 @default.
- W2049279006 hasAuthorship W2049279006A5010148762 @default.
- W2049279006 hasAuthorship W2049279006A5042232456 @default.
- W2049279006 hasConcept C141071460 @default.
- W2049279006 hasConcept C181199279 @default.
- W2049279006 hasConcept C185592680 @default.
- W2049279006 hasConcept C2775838275 @default.
- W2049279006 hasConcept C2776151105 @default.
- W2049279006 hasConcept C2777104736 @default.
- W2049279006 hasConcept C2777352226 @default.
- W2049279006 hasConcept C2777504301 @default.
- W2049279006 hasConcept C2778004101 @default.
- W2049279006 hasConcept C2778257484 @default.
- W2049279006 hasConcept C2778760513 @default.
- W2049279006 hasConcept C2780428090 @default.
- W2049279006 hasConcept C2780827179 @default.
- W2049279006 hasConcept C2780829032 @default.
- W2049279006 hasConcept C2781242345 @default.
- W2049279006 hasConcept C538909803 @default.
- W2049279006 hasConcept C55493867 @default.
- W2049279006 hasConcept C71924100 @default.
- W2049279006 hasConcept C98274493 @default.
- W2049279006 hasConceptScore W2049279006C141071460 @default.
- W2049279006 hasConceptScore W2049279006C181199279 @default.
- W2049279006 hasConceptScore W2049279006C185592680 @default.
- W2049279006 hasConceptScore W2049279006C2775838275 @default.
- W2049279006 hasConceptScore W2049279006C2776151105 @default.
- W2049279006 hasConceptScore W2049279006C2777104736 @default.
- W2049279006 hasConceptScore W2049279006C2777352226 @default.
- W2049279006 hasConceptScore W2049279006C2777504301 @default.
- W2049279006 hasConceptScore W2049279006C2778004101 @default.
- W2049279006 hasConceptScore W2049279006C2778257484 @default.
- W2049279006 hasConceptScore W2049279006C2778760513 @default.
- W2049279006 hasConceptScore W2049279006C2780428090 @default.
- W2049279006 hasConceptScore W2049279006C2780827179 @default.
- W2049279006 hasConceptScore W2049279006C2780829032 @default.
- W2049279006 hasConceptScore W2049279006C2781242345 @default.
- W2049279006 hasConceptScore W2049279006C538909803 @default.
- W2049279006 hasConceptScore W2049279006C55493867 @default.
- W2049279006 hasConceptScore W2049279006C71924100 @default.
- W2049279006 hasConceptScore W2049279006C98274493 @default.
- W2049279006 hasIssue "3" @default.
- W2049279006 hasLocation W20492790061 @default.
- W2049279006 hasLocation W20492790062 @default.
- W2049279006 hasOpenAccess W2049279006 @default.
- W2049279006 hasPrimaryLocation W20492790061 @default.
- W2049279006 hasRelatedWork W1566607623 @default.
- W2049279006 hasRelatedWork W2012945609 @default.
- W2049279006 hasRelatedWork W2027795887 @default.
- W2049279006 hasRelatedWork W2056187023 @default.
- W2049279006 hasRelatedWork W2083154293 @default.
- W2049279006 hasRelatedWork W2115902097 @default.
- W2049279006 hasRelatedWork W2186050858 @default.
- W2049279006 hasRelatedWork W2948950651 @default.
- W2049279006 hasRelatedWork W1775552615 @default.
- W2049279006 hasRelatedWork W1932750572 @default.
- W2049279006 hasVolume "19" @default.
- W2049279006 isParatext "false" @default.
- W2049279006 isRetracted "false" @default.
- W2049279006 magId "2049279006" @default.
- W2049279006 workType "article" @default.