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- W2049321490 abstract "A single oral dose of 50 mg/kg of DDT administered to mice 18 hr prior to experimentation was found to reduce glucose tolerance without affecting the basal blood concentration of glucose. Also, the treatment inhibited both d-glucose and tolbutamide-stimulated insulin release by isolated pancreatic islets. Hyperglycemia was not noted during the 18-hr period after DDT. The effect of DDT on glucose tolerance persisted for at least 1 week. Reduced pancreatic secretory activity after DDT administration is consistent with the increased activity of gluconeogenic enzymes as well as decreased glycogen synthetase activity reported by earlier workers." @default.
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- W2049321490 date "1977-01-01" @default.
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- W2049321490 title "The inhibitoty effect of DDT on insulin secretion in mice" @default.
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- W2049321490 doi "https://doi.org/10.1016/0041-008x(77)90179-x" @default.
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