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• W2049335390 abstract "In the present work, a highly sensitive and specific fluorescent biosensor for blood glucose monitoring is developed based on hemin-functionalized graphene quantum dots (GQDs) and glucose oxidase (GOx) system. The GQDs which are simply prepared by pyrolyzing citric acid exhibit strong fluorescence and good water-solubility. Due to the noncovalent assembly between hemin and GQDs, the addition of hemin can make hydrogen peroxide (H2O2) to destroy the passivated surface of GQDs, leading to significant fluorescence quenching of GQDs. Based on this effect, a novel fluorescent platform is proposed for the sensing of glucose. Under the optimized conditions, the linear range of glucose is from 9 to 300 μM, and the limit of detection is 0.1 μM. As unique properties of GQDs, the proposed biosensor is green, simple, cost-efficient, and it is successfully applied to the determination of glucose in human serum. In addition, the proposed method provides a new pathway to further design the biosensors based on the assembly of GQDs with hemin for detection of biomolecules." @default.
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• W2049335390 date "2014-01-01" @default.
• W2049335390 modified "2023-10-11" @default.
• W2049335390 title "Fluorescent blood glucose monitor by hemin-functionalized graphene quantum dots based sensing system" @default.
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• W2049335390 doi "https://doi.org/10.1016/j.aca.2013.11.059" @default.
• W2049335390 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24439507" @default.
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