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• W2049344791 abstract "A parallel synthesis of racemic himbacine analogs was carried out by N-alkylation of various commercially available cyclic amine derivatives with the alkylating agent 4 which bears the tricyclic unit of himbacine. Several of these analogs have potency comparable to that of himbacine, albeit lacking the desired selectivity. Structure-activity relationship studies support the existence of a hydrophobic pocket in the receptor where the piperidine ring of dihydrohimbacine binds." @default.
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• W2049344791 date "1999-03-01" @default.
• W2049344791 modified "2023-09-24" @default.
• W2049344791 title "Design, synthesis, and structure-activity relationship studies of himbacine derived muscarinic receptor antagonists" @default.
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• W2049344791 doi "https://doi.org/10.1016/s0960-894x(99)00101-8" @default.
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