FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049347612> ?p ?o ?g. }

• W2049347612 abstract "Only 15 to 20% of acute promyelocytic leukaemia (APL) patients are older than 60 years, and the characteristics and outcome of APL in that age range are not well known. Published studies show that APL in elderly patients has haematological features similar to those of APL in younger patients. However, using the current combination of all-trans retinoic acid (ATRA) and anthracycline-based chemotherapy, the outcome for these patients, although it has much improved, remains less favourable than that for younger patients. This is due to a higher incidence of early deaths and deaths in complete remission (CR), during consolidation chemotherapy courses, whereas the relapse rate appears similar in older and younger adults. Treatment approaches with more limited myelosuppression, especially consolidation chemotherapy with an anthracycline alone (without Ara-C), low-dose maintenance treatment with 6-mercaptopurine, methotrexate and ATRA, and consolidation with arsenic trioxide, should be tested especially in elderly patients in order to replace more toxic 'classical' anthracycline-Ara-C consolidation treatment, after achieving CR with ATRA." @default.
• W2049347612 created "2016-06-24" @default.
• W2049347612 creator A5014838075 @default.
• W2049347612 creator A5017435311 @default.
• W2049347612 creator A5052673276 @default.
• W2049347612 date "2003-09-01" @default.
• W2049347612 modified "2023-10-14" @default.
• W2049347612 title "Treatment of older adults with acute promyelocytic leukaemia" @default.
• W2049347612 cites W115875242 @default.
• W2049347612 cites W1515269506 @default.
• W2049347612 cites W1531493896 @default.
• W2049347612 cites W1576475831 @default.
• W2049347612 cites W1692919389 @default.
• W2049347612 cites W1790757523 @default.
• W2049347612 cites W1931891535 @default.
• W2049347612 cites W1948143034 @default.
• W2049347612 cites W1980607962 @default.
• W2049347612 cites W1982426748 @default.
• W2049347612 cites W2025373117 @default.
• W2049347612 cites W2042425638 @default.
• W2049347612 cites W2094836482 @default.
• W2049347612 cites W2128291738 @default.
• W2049347612 cites W2142423276 @default.
• W2049347612 cites W2144960464 @default.
• W2049347612 cites W2146450867 @default.
• W2049347612 cites W2146907085 @default.
• W2049347612 cites W2162974504 @default.
• W2049347612 cites W2333481337 @default.
• W2049347612 cites W2334200141 @default.
• W2049347612 cites W2461079032 @default.
• W2049347612 cites W2474307831 @default.
• W2049347612 cites W432680243 @default.
• W2049347612 cites W570370693 @default.
• W2049347612 doi "https://doi.org/10.1016/s1521-6926(03)00044-6" @default.
• W2049347612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12935965" @default.
• W2049347612 hasPublicationYear "2003" @default.
• W2049347612 type Work @default.
• W2049347612 sameAs 2049347612 @default.
• W2049347612 citedByCount "17" @default.
• W2049347612 countsByYear W20493476122012 @default.
• W2049347612 countsByYear W20493476122013 @default.
• W2049347612 countsByYear W20493476122014 @default.
• W2049347612 countsByYear W20493476122015 @default.
• W2049347612 countsByYear W20493476122017 @default.
• W2049347612 crossrefType "journal-article" @default.
• W2049347612 hasAuthorship W2049347612A5014838075 @default.
• W2049347612 hasAuthorship W2049347612A5017435311 @default.
• W2049347612 hasAuthorship W2049347612A5052673276 @default.
• W2049347612 hasConcept C104317684 @default.
• W2049347612 hasConcept C121608353 @default.
• W2049347612 hasConcept C126322002 @default.
• W2049347612 hasConcept C141071460 @default.
• W2049347612 hasConcept C143998085 @default.
• W2049347612 hasConcept C185592680 @default.
• W2049347612 hasConcept C191897082 @default.
• W2049347612 hasConcept C192562407 @default.
• W2049347612 hasConcept C2776601000 @default.
• W2049347612 hasConcept C2776694085 @default.
• W2049347612 hasConcept C2776802502 @default.
• W2049347612 hasConcept C2780386689 @default.
• W2049347612 hasConcept C2781059491 @default.
• W2049347612 hasConcept C2781121885 @default.
• W2049347612 hasConcept C502230775 @default.
• W2049347612 hasConcept C530470458 @default.
• W2049347612 hasConcept C55493867 @default.
• W2049347612 hasConcept C71924100 @default.
• W2049347612 hasConceptScore W2049347612C104317684 @default.
• W2049347612 hasConceptScore W2049347612C121608353 @default.
• W2049347612 hasConceptScore W2049347612C126322002 @default.
• W2049347612 hasConceptScore W2049347612C141071460 @default.
• W2049347612 hasConceptScore W2049347612C143998085 @default.
• W2049347612 hasConceptScore W2049347612C185592680 @default.
• W2049347612 hasConceptScore W2049347612C191897082 @default.
• W2049347612 hasConceptScore W2049347612C192562407 @default.
• W2049347612 hasConceptScore W2049347612C2776601000 @default.
• W2049347612 hasConceptScore W2049347612C2776694085 @default.
• W2049347612 hasConceptScore W2049347612C2776802502 @default.
• W2049347612 hasConceptScore W2049347612C2780386689 @default.
• W2049347612 hasConceptScore W2049347612C2781059491 @default.
• W2049347612 hasConceptScore W2049347612C2781121885 @default.
• W2049347612 hasConceptScore W2049347612C502230775 @default.
• W2049347612 hasConceptScore W2049347612C530470458 @default.
• W2049347612 hasConceptScore W2049347612C55493867 @default.
• W2049347612 hasConceptScore W2049347612C71924100 @default.
• W2049347612 hasLocation W20493476121 @default.
• W2049347612 hasLocation W20493476122 @default.
• W2049347612 hasOpenAccess W2049347612 @default.
• W2049347612 hasPrimaryLocation W20493476121 @default.
• W2049347612 hasRelatedWork W111885052 @default.
• W2049347612 hasRelatedWork W2025373117 @default.
• W2049347612 hasRelatedWork W2037067814 @default.
• W2049347612 hasRelatedWork W2099619147 @default.
• W2049347612 hasRelatedWork W2127615489 @default.
• W2049347612 hasRelatedWork W2370586326 @default.
• W2049347612 hasRelatedWork W2608155461 @default.
• W2049347612 hasRelatedWork W2800815670 @default.
• W2049347612 hasRelatedWork W3030350200 @default.
• W2049347612 hasRelatedWork W3031387768 @default.
• W2049347612 isParatext "false" @default.
• W2049347612 isRetracted "false" @default.

• next