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- W2049362885 abstract "Abstract Objective: To determine and compare the distribution of Porphyromonas gingivalis fimA genotypes in type 2 diabetes mellitus (T2DM) patients affected by periodontitis, using non‐diabetic subjects with and without periodontitis as control groups. Material and Methods: This study involved 75 subjects divided into three groups of 25 subjects each: Group 1 (non‐T2DM without periodontitis), Group 2 (non‐T2DM with periodontitis) and Group 3 (T2DM with periodontitis). The outcome variable was periodontitis, and explanatory variables were age, sex, T2DM and specific P. gingivalis fimA genotypes. Results: In non‐T2DM subjects with healthy periodontal tissues, type I fimA was the most frequently detected individually (40%) or in combinations (40%). In non‐T2DM subjects with periodontitis, the most frequently detected type was Ib individually (20%) or in combinations (36%). In T2DM patients with periodontitis, the most frequently detected types were types I (20%) and III (20%), but there was no statistical difference ( p >0.05) with non‐T2DM periodontitis subjects. Conclusions: Type I genotype was more frequently detected in periodontally healthy sites from non‐T2DM subjects than in periodontitis sites from either subjects with or without T2DM. However, in sites affected by periodontitis from T2DM subjects the predominating types were I and III, which are less virulent strains of P. gingivalis ." @default.
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- W2049362885 date "2006-11-24" @default.
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- W2049362885 title "Distribution of Genotypes of Porphyromonas gingivalis in Type 2 Diabetic Patients with Periodontitis in Mexico" @default.
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- W2049362885 doi "https://doi.org/10.1111/j.1600-051x.2006.01011.x" @default.
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