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- W2049397408 abstract "AN increasing number of drugs interact with warfarin sodium to alter the plasma prothrombin-complex content.1 2 3 4 Recently, Koch-Weser5 suggested that in some patients quinidine sulfate acts synergistically with warfarin to prolong the plasma prothrombin time.Case ReportA 48-year-old man was admitted to the Peter Bent Brigham Hospital in November, 1967, for aortic-valve replacement. In the previous August a diagnosis of aortic stenosis and coronary-artery disease was made, and quinidine, 200 mg by mouth 3 times daily, was given for premature atrial contractions. There was no history of liver disorder. Physical examination showed a murmur consistent with aortic stenosis.Urinalysis, complete . . ." @default.
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- W2049397408 date "1969-03-27" @default.
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- W2049397408 title "Possible Quinidine-Induced Hemorrhage in a Patient on Warfarin Sodium" @default.
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- W2049397408 doi "https://doi.org/10.1056/nejm196903272801309" @default.
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