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- W2049430405 abstract "Two strains of mice, Balb/c and B10/D2, that were maintained on two different diets were evaluated for their susceptibility to herpes simplex virus type 1 infection (HSV). The diets were a Purina laboratory chow and a Teklad egg white diet. These diets are assumed to be nutritionally complete. Both mouse strains maintained on the Teklad diet were significantly more resistant to lethal HSV infection. Weight gain and food consumption between dietary groups were equivalent. At least 3-fold higher virus titers were found in peritoneum, liver, spleen, spinal cord and brain of animals on the Purina diet. Time of viral appearance in the central nervous system corresponded to onset of symptoms of encephalitis. We conclude that alteration in nutritional intake is responsible for differential survival rates. The factor(s) in these diets that account for the variance in resistance to HSV-1 infection is not known." @default.
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- W2049430405 date "1994-04-01" @default.
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- W2049430405 title "Effect of diet on herpes simplex virus, type 1, infection in mice" @default.
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- W2049430405 doi "https://doi.org/10.1016/s0271-5317(05)80218-0" @default.
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