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- W2049470127 abstract "A new approach to the Fischer-indole synthesis is reported that uses the reactive intermediate benzyne. The addition of N-tosyl hydrazones to arynes, generated through fluoride activation of 2-(trimethylsilyl)phenyl triflate precursors, leads to efficient N-arylation. Addition of a Lewis acid to the same reaction pot then affords N-tosylindole products via Fischer cyclization." @default.
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- W2049470127 date "2011-06-14" @default.
- W2049470127 modified "2023-10-15" @default.
- W2049470127 title "The Benzyne Fischer-Indole Reaction" @default.
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- W2049470127 doi "https://doi.org/10.1021/ol201413r" @default.
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