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- W2049558840 abstract "AbstractIn our previous studies, we clarified that enteric granules are an appropriate dosage form for lansoprazole, and we demonstrated that enteric granules could be produced when magnesium carbonate was added as an alkaline stabilizer.These granules however were found to be some unstable under severe conditions because some of the excipients are incompatible with lansoprazole. We therefore attempted granulation not using these incompatible excipients and could obtain more stable enteric granules using a centrifugal fluid-bed granulator instead of an extruder-spheronizer. We also compared the absorption and dissolution properties of the enteric granules manufactured by these two methods." @default.
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- W2049558840 date "1994-01-01" @default.
- W2049558840 modified "2023-09-26" @default.
- W2049558840 title "Manufacturing Method of Stable Enteric Granules of a New Antiulcer Drug (Lansoprazole)" @default.
- W2049558840 cites W1985110450 @default.
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- W2049558840 doi "https://doi.org/10.3109/03639049409050206" @default.
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