FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049572301> ?p ?o ?g. }

• W2049572301 endingPage "86" @default.
• W2049572301 startingPage "80" @default.
• W2049572301 abstract "Inhibitors of DNA repair proteins have been used in cancer therapy, mostly to potentiate the effects of cytotoxic agents. However, tumor cells frequently exhibit deficiencies in the signalling or repair of DNA damage. These deficiencies probably contribute to pathogenesis of the disease, but they also present an opportunity to target the tumor. Recently, inhibitors of poly(ADP-ribose) polymerase (PARP) have been shown to be highly selective for tumor cells with defects in the repair of double-strand DNA breaks (DSBs) by homologous recombination, particularly in the context of BRCA1 or BRCA2 mutation. It seems likely that other DNA repair processes can be targeted in a similar manner. These synthetic lethal approaches highlight how an understanding of DNA repair processes can be used in the development of novel cancer treatments." @default.
• W2049572301 created "2016-06-24" @default.
• W2049572301 creator A5033773451 @default.
• W2049572301 creator A5040450413 @default.
• W2049572301 creator A5058973407 @default.
• W2049572301 date "2008-02-01" @default.
• W2049572301 modified "2023-09-25" @default.
• W2049572301 title "DNA repair deficiency as a therapeutic target in cancer" @default.
• W2049572301 cites W1483706688 @default.
• W2049572301 cites W1490502986 @default.
• W2049572301 cites W1523531555 @default.
• W2049572301 cites W1825629489 @default.
• W2049572301 cites W1964729065 @default.
• W2049572301 cites W1968960110 @default.
• W2049572301 cites W1972769310 @default.
• W2049572301 cites W1973268287 @default.
• W2049572301 cites W1977923363 @default.
• W2049572301 cites W1979800136 @default.
• W2049572301 cites W1985804387 @default.
• W2049572301 cites W1989116759 @default.
• W2049572301 cites W1992181783 @default.
• W2049572301 cites W1993031792 @default.
• W2049572301 cites W2002150942 @default.
• W2049572301 cites W2002332446 @default.
• W2049572301 cites W2002821487 @default.
• W2049572301 cites W2009007206 @default.
• W2049572301 cites W2011912935 @default.
• W2049572301 cites W2013970469 @default.
• W2049572301 cites W2022327201 @default.
• W2049572301 cites W2025412572 @default.
• W2049572301 cites W2026566313 @default.
• W2049572301 cites W2026895762 @default.
• W2049572301 cites W2049372916 @default.
• W2049572301 cites W2059971436 @default.
• W2049572301 cites W2069385762 @default.
• W2049572301 cites W2077859982 @default.
• W2049572301 cites W2095075630 @default.
• W2049572301 cites W2096136751 @default.
• W2049572301 cites W2097205092 @default.
• W2049572301 cites W2101988823 @default.
• W2049572301 cites W2105100844 @default.
• W2049572301 cites W2121371748 @default.
• W2049572301 cites W2124156743 @default.
• W2049572301 cites W2127884528 @default.
• W2049572301 cites W2132281009 @default.
• W2049572301 cites W2132329433 @default.
• W2049572301 cites W2138277779 @default.
• W2049572301 cites W2140447069 @default.
• W2049572301 cites W2142658272 @default.
• W2049572301 cites W2143434102 @default.
• W2049572301 cites W2144851947 @default.
• W2049572301 cites W2146054274 @default.
• W2049572301 cites W2259017169 @default.
• W2049572301 cites W2570014192 @default.
• W2049572301 doi "https://doi.org/10.1016/j.gde.2008.01.016" @default.
• W2049572301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18343102" @default.
• W2049572301 hasPublicationYear "2008" @default.
• W2049572301 type Work @default.
• W2049572301 sameAs 2049572301 @default.
• W2049572301 citedByCount "159" @default.
• W2049572301 countsByYear W20495723012012 @default.
• W2049572301 countsByYear W20495723012013 @default.
• W2049572301 countsByYear W20495723012014 @default.
• W2049572301 countsByYear W20495723012015 @default.
• W2049572301 countsByYear W20495723012016 @default.
• W2049572301 countsByYear W20495723012017 @default.
• W2049572301 countsByYear W20495723012018 @default.
• W2049572301 countsByYear W20495723012019 @default.
• W2049572301 countsByYear W20495723012020 @default.
• W2049572301 countsByYear W20495723012021 @default.
• W2049572301 countsByYear W20495723012022 @default.
• W2049572301 crossrefType "journal-article" @default.
• W2049572301 hasAuthorship W2049572301A5033773451 @default.
• W2049572301 hasAuthorship W2049572301A5040450413 @default.
• W2049572301 hasAuthorship W2049572301A5058973407 @default.
• W2049572301 hasConcept C102744134 @default.
• W2049572301 hasConcept C121608353 @default.
• W2049572301 hasConcept C134935766 @default.
• W2049572301 hasConcept C143425029 @default.
• W2049572301 hasConcept C151730666 @default.
• W2049572301 hasConcept C182979987 @default.
• W2049572301 hasConcept C2778502085 @default.
• W2049572301 hasConcept C2779343474 @default.
• W2049572301 hasConcept C502942594 @default.
• W2049572301 hasConcept C54355233 @default.
• W2049572301 hasConcept C552990157 @default.
• W2049572301 hasConcept C82381507 @default.
• W2049572301 hasConcept C86803240 @default.
• W2049572301 hasConcept C96232424 @default.
• W2049572301 hasConceptScore W2049572301C102744134 @default.
• W2049572301 hasConceptScore W2049572301C121608353 @default.
• W2049572301 hasConceptScore W2049572301C134935766 @default.
• W2049572301 hasConceptScore W2049572301C143425029 @default.
• W2049572301 hasConceptScore W2049572301C151730666 @default.
• W2049572301 hasConceptScore W2049572301C182979987 @default.
• W2049572301 hasConceptScore W2049572301C2778502085 @default.
• W2049572301 hasConceptScore W2049572301C2779343474 @default.
• W2049572301 hasConceptScore W2049572301C502942594 @default.

• next