Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049596904> ?p ?o ?g. }
- W2049596904 endingPage "54" @default.
- W2049596904 startingPage "51" @default.
- W2049596904 abstract "Histamine is a regulator of gastric acid secretion, which is involved in the development of duodenal ulcer (DU). Histamine is metabolized by both histamine N-methyltransferase (HNMT) and diamine oxidase, and its local action is terminated primarily by methylation which is catalyzed by HNMT.Polymerase chain reaction-restriction fragment length polymorphism assay was used to identify the polymorphism of the point mutation C314T of HNMT gene of 498 Chinese patients with DU and 151 healthy individuals.In normal controls, the allele frequency of HNMT T314 was 3.3%, which was significantly lower than American Caucasians. The HNMT T314 allele was detected in 3.5% of the DU patients. In cases and controls, the frequency of C/C genotypes were 93.0% and 93.4%, respectively. The HNMT T/T genotype was not found in this population. No significant differences were seen in both genotype frequencies and allele frequencies between DU groups and controls. After stratified by H. pylori infection, they also could not reach significant differences in our current study.The HNMT T314 allele frequency is lower in Chinese population than in American Caucasians. No association can be found in the involvement of HNMT C314T polymorphism in the susceptibility to duodenal ulcer." @default.
- W2049596904 created "2016-06-24" @default.
- W2049596904 creator A5019237726 @default.
- W2049596904 creator A5042984215 @default.
- W2049596904 creator A5062179244 @default.
- W2049596904 creator A5081860423 @default.
- W2049596904 date "2008-03-01" @default.
- W2049596904 modified "2023-10-14" @default.
- W2049596904 title "C314T polymorphism in histamine N-methyltransferase gene and susceptibility to duodenal ulcer in Chinese population" @default.
- W2049596904 cites W1954568456 @default.
- W2049596904 cites W1965981355 @default.
- W2049596904 cites W1976612144 @default.
- W2049596904 cites W2001158424 @default.
- W2049596904 cites W2004573492 @default.
- W2049596904 cites W2006262709 @default.
- W2049596904 cites W2017363750 @default.
- W2049596904 cites W2019042978 @default.
- W2049596904 cites W2020756372 @default.
- W2049596904 cites W2022124773 @default.
- W2049596904 cites W2023837396 @default.
- W2049596904 cites W2027337176 @default.
- W2049596904 cites W2032292919 @default.
- W2049596904 cites W2039610177 @default.
- W2049596904 cites W2045909856 @default.
- W2049596904 cites W2048442242 @default.
- W2049596904 cites W2061555752 @default.
- W2049596904 cites W2079713563 @default.
- W2049596904 cites W2086534539 @default.
- W2049596904 cites W2094119569 @default.
- W2049596904 cites W2103171526 @default.
- W2049596904 cites W2119604949 @default.
- W2049596904 cites W2127353671 @default.
- W2049596904 cites W2139716382 @default.
- W2049596904 cites W2155979210 @default.
- W2049596904 cites W2162208188 @default.
- W2049596904 cites W2330799737 @default.
- W2049596904 cites W2912042551 @default.
- W2049596904 cites W96938513 @default.
- W2049596904 doi "https://doi.org/10.1016/j.cca.2007.11.022" @default.
- W2049596904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18086566" @default.
- W2049596904 hasPublicationYear "2008" @default.
- W2049596904 type Work @default.
- W2049596904 sameAs 2049596904 @default.
- W2049596904 citedByCount "6" @default.
- W2049596904 countsByYear W20495969042013 @default.
- W2049596904 countsByYear W20495969042019 @default.
- W2049596904 countsByYear W20495969042021 @default.
- W2049596904 countsByYear W20495969042023 @default.
- W2049596904 crossrefType "journal-article" @default.
- W2049596904 hasAuthorship W2049596904A5019237726 @default.
- W2049596904 hasAuthorship W2049596904A5042984215 @default.
- W2049596904 hasAuthorship W2049596904A5062179244 @default.
- W2049596904 hasAuthorship W2049596904A5081860423 @default.
- W2049596904 hasConcept C104317684 @default.
- W2049596904 hasConcept C1122143 @default.
- W2049596904 hasConcept C134018914 @default.
- W2049596904 hasConcept C135763542 @default.
- W2049596904 hasConcept C153911025 @default.
- W2049596904 hasConcept C170493617 @default.
- W2049596904 hasConcept C180754005 @default.
- W2049596904 hasConcept C181199279 @default.
- W2049596904 hasConcept C187507357 @default.
- W2049596904 hasConcept C2776409635 @default.
- W2049596904 hasConcept C2776885963 @default.
- W2049596904 hasConcept C2779053737 @default.
- W2049596904 hasConcept C2908647359 @default.
- W2049596904 hasConcept C34400551 @default.
- W2049596904 hasConcept C37463918 @default.
- W2049596904 hasConcept C54355233 @default.
- W2049596904 hasConcept C55493867 @default.
- W2049596904 hasConcept C71924100 @default.
- W2049596904 hasConcept C86803240 @default.
- W2049596904 hasConcept C99454951 @default.
- W2049596904 hasConceptScore W2049596904C104317684 @default.
- W2049596904 hasConceptScore W2049596904C1122143 @default.
- W2049596904 hasConceptScore W2049596904C134018914 @default.
- W2049596904 hasConceptScore W2049596904C135763542 @default.
- W2049596904 hasConceptScore W2049596904C153911025 @default.
- W2049596904 hasConceptScore W2049596904C170493617 @default.
- W2049596904 hasConceptScore W2049596904C180754005 @default.
- W2049596904 hasConceptScore W2049596904C181199279 @default.
- W2049596904 hasConceptScore W2049596904C187507357 @default.
- W2049596904 hasConceptScore W2049596904C2776409635 @default.
- W2049596904 hasConceptScore W2049596904C2776885963 @default.
- W2049596904 hasConceptScore W2049596904C2779053737 @default.
- W2049596904 hasConceptScore W2049596904C2908647359 @default.
- W2049596904 hasConceptScore W2049596904C34400551 @default.
- W2049596904 hasConceptScore W2049596904C37463918 @default.
- W2049596904 hasConceptScore W2049596904C54355233 @default.
- W2049596904 hasConceptScore W2049596904C55493867 @default.
- W2049596904 hasConceptScore W2049596904C71924100 @default.
- W2049596904 hasConceptScore W2049596904C86803240 @default.
- W2049596904 hasConceptScore W2049596904C99454951 @default.
- W2049596904 hasIssue "1-2" @default.
- W2049596904 hasLocation W20495969041 @default.
- W2049596904 hasLocation W20495969042 @default.
- W2049596904 hasOpenAccess W2049596904 @default.
- W2049596904 hasPrimaryLocation W20495969041 @default.